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The Helix-Loop-Helix Motif

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Nucleic Acids and Molecular Biology

Part of the book series: Nucleic Acids and Molecular Biology ((NUCLEIC,volume 6))

Abstract

Recently, families of transcription factors have been identified, having in common a region of homology in their DNA binding domain. Examples are DNA binding proteins containing zinc fingers, homeo-boxes, leucine zippers, etc. In this review I will discuss the structure and function of a new class of proteins that contain a region of homology in their DNA binding and dimerization domain, termed the helix-loop-helix (HLH) motif.

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Author information

Authors and Affiliations

  1. Department of Biology, 0116 and Center for Molecular Genetics, University of California, San Diego, La Jolla, CA, 92093-0116, USA

    C. Murre

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  1. C. Murre
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Editor information

Editors and Affiliations

  1. Max-Planck-Institut für Experimentelle Medizin, Hermann-Rein-Straße 3, W-3400, Göttingen, Germany

    Fritz Eckstein

  2. Biochemistry Department, University of Dundee, DD1 4HN, Dundee, UK

    David M. J. Lilley

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© 1992 Springer-Verlag Berlin Heidelberg

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Murre, C. (1992). The Helix-Loop-Helix Motif. In: Eckstein, F., Lilley, D.M.J. (eds) Nucleic Acids and Molecular Biology. Nucleic Acids and Molecular Biology, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77356-3_6

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  • DOI: https://doi.org/10.1007/978-3-642-77356-3_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77358-7

  • Online ISBN: 978-3-642-77356-3

  • eBook Packages: Springer Book Archive

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