Isoelectric Focusing of Inter-Alpha-Trypsin Inhibitor (ITI)
Part of the
Advances in Forensic Haemogenetics
book series (HAEMOGENETICS, volume 4)
The genetic polymorphism of human plasma inter-alpha-trypsin inhibitor (ITI), a serine protease inhibitor, was first described by Vogt and Cleve (1990). Both precise subunit composition and chromosomal assignment of the corresponding locus remain under investigation (SchreitmUller et al., 1987, Luckenbach et al., 1991). In this work we present formal and population genetics results obtained in families from SW Germany and NW Portugal.
KeywordsGenetic Polymorphism Mating Type Serine Protease Inhibitor Monomeric Protein Formal Hypothesis
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Schreitmüller T, Hochstrasser K, Reisinger PWM, Wachter E, Gebhard W (1987) cDNA cloning of human inter-alpha-trypsin inhibitor discloses three different proteins. Biol Chem Hoppe Seyler 368: 963–970PubMedCrossRefGoogle Scholar
Luckenbach C, Kömpf J, Ritter H (1991). Genetic polymorphism of inter-alphatrypsin-inhibitor (ITI): formal genetics and linkage analysis. Hum Genet 87: 89–90PubMedCrossRefGoogle Scholar
Vogt U, Cleve H (1990) A “new” genetic polymorphism of a human serum protein: inter-alpha-trypsin inhibitor. Hum Genet 84: 151–154PubMedGoogle Scholar
© Springer-Verlag Berlin Heidelberg 1992