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Isoelectric Focusing of Inter-Alpha-Trypsin Inhibitor (ITI)

  • C. Luckenbach
  • J. Kömpf
  • A. Amorim
  • J. Rocha
  • A. Trein
Part of the Advances in Forensic Haemogenetics book series (HAEMOGENETICS, volume 4)

Abstract

The genetic polymorphism of human plasma inter-alpha-trypsin inhibitor (ITI), a serine protease inhibitor, was first described by Vogt and Cleve (1990). Both precise subunit composition and chromosomal assignment of the corresponding locus remain under investigation (SchreitmUller et al., 1987, Luckenbach et al., 1991). In this work we present formal and population genetics results obtained in families from SW Germany and NW Portugal.

Keywords

Genetic Polymorphism Mating Type Serine Protease Inhibitor Monomeric Protein Formal Hypothesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Schreitmüller T, Hochstrasser K, Reisinger PWM, Wachter E, Gebhard W (1987) cDNA cloning of human inter-alpha-trypsin inhibitor discloses three different proteins. Biol Chem Hoppe Seyler 368: 963–970PubMedCrossRefGoogle Scholar
  2. Luckenbach C, Kömpf J, Ritter H (1991). Genetic polymorphism of inter-alphatrypsin-inhibitor (ITI): formal genetics and linkage analysis. Hum Genet 87: 89–90PubMedCrossRefGoogle Scholar
  3. Vogt U, Cleve H (1990) A “new” genetic polymorphism of a human serum protein: inter-alpha-trypsin inhibitor. Hum Genet 84: 151–154PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • C. Luckenbach
    • 1
  • J. Kömpf
    • 1
  • A. Amorim
    • 2
  • J. Rocha
    • 2
  • A. Trein
    • 1
  1. 1.Inst.Anthropologie und HumangenetikF.R.Germany
  2. 2.Inst.AntropologiaUniv.PortoPortoPortugal

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