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Determination of C1R Types in Bloodstains

  • A. Kido
  • N. Komatsu
  • Y. Kimura
  • M. Oya
Conference paper
Part of the Advances in Forensic Haemogenetics book series (HAEMOGENETICS, volume 4)

Abstract

Genetic polymorphism of the C1R subcomponent was first discovered by Kamboh and Ferrell (1986). Using isoelectric focusing and immunoblotting, they described 2 common alleles C1R*1 and C1R*2 in native plasma samples from US whites and US blacks. Besides these 2 common alleles, several further variant alleles have been detected in a variety of ethnic groups by treating plasma samples with neuraminidase (Kamboh et al. 1988, 1989; Nakamura et al. 1988).

Keywords

Common Allele Clostridium Perfringens Legal Medicine Large Genetic Variation Treat Plasma Sample 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Reference

  1. Kamboh MI, Ferrell RE (1986) Genetic studies of low abundance human plasma proteins. III. Polymorphism of the C1R subcomponent of the first complement component. Am J Hum Genet 39: 826–831PubMedGoogle Scholar
  2. Kamboh MI, Lyons L, Ferrell RE (1988) Genetic studies of lowabundance human plasma proteins. IX. A new allele at the complement subcomponent C1R structural locus. Hum Genet 81: 93–94PubMedCrossRefGoogle Scholar
  3. Kamboh MI, Lyons LA, Ferrell RE (1989) Genetic studies of lowabundance human plasma proteins. XIII. Population genetics of C1R complement subcomponent and description of a new variants. Am J Hum Genet 44: 148–153PubMedGoogle Scholar
  4. Kido A, Komatsu N, Kimura Y, Oya M (1991) C1R subcomponent polymorphism in Japanese: Description of a new allele. Hum Hered 41: 129–133PubMedCrossRefGoogle Scholar
  5. Nakamura S, Ohue O, Akiyama K, Abe K (1988) Genetic polymorphism of human C1R subcomponent of the first complement component in the Japanese population. Forensic Sci Int 39: 71–76PubMedCrossRefGoogle Scholar
  6. Nakamura S, Omoto K, Ohue O, Yamashita K, Ochi J, Akiyama K, Sawaguchi A (1990) C1R polymorphism in the Japanese population. Proceedings of the First International Symposium Advances in Legal Medicine pp 438–440Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • A. Kido
    • 1
  • N. Komatsu
    • 1
  • Y. Kimura
    • 1
  • M. Oya
    • 1
  1. 1.Department of Legal MedicineYamanashi Medical UniversityYamanashi-kenJapan

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