The Role of T Cell Immunity in Control of Herpes Simplex Virus

  • D. S. Schmid
  • B. T. Rouse
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 179)


Since their characterization in the mid-1960s, thymus-derived, or T lymphocytes have been shown to participate in virtually every process of mammalian immunity. This participation can take the form of response modification, mediated by secreted physiologically active cytokines, or direct effector activity, as exemplified by cell-mediated cytolysis and the inhibition of viral replication by interferon-γ (IFN-γ).


Major Histocompatibility Complex Herpes Simplex Virus Herpes Simplex Virus Type Herpes Simplex Virus Infection Major Histocompatibility Complex Antigen 
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Copyright information

© Springer-Verlag Berlin, Heidelberg 1992

Authors and Affiliations

  • D. S. Schmid
    • 1
  • B. T. Rouse
    • 2
  1. 1.Viral Exanthems and Herpesvirus BranchAtlantaUSA
  2. 2.Department of Microbiology, College of Veterinary MedicineUniversity of TennesseeKnoxvilleUSA

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