Abstract
Although the immunological basis of protection from shigellosis is poorly understood, it is likely that secretory immunoglobulin A (IgA) on mucosal surfaces and mucosal lymphocytes in the intestine play important roles in this process. Therefore, a summary of the possible protective roles of lymphocytes and immunoglobulin will provide a context for the subsequent discussion of Shigella vaccine development.
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© 1992 Springer-Verlag Berlin Heidelberg
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Hale, T.L., Keren, D.F. (1992). Pathogenesis and Immunology in Shigellosis: Applications for Vaccine Development. In: Sansonetti, P.J. (eds) Pathogenesis of Shigellosis. Current Topics in Microbiology and Immunology, vol 180. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77238-2_6
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DOI: https://doi.org/10.1007/978-3-642-77238-2_6
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