Molecular and Cellular Biology of Shigella flexneri Invasiveness: From Cell Assay Systems to Shigellosis

  • P. J. Sansonetti
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 180)


Also known as bacillary dysentery, shigellosis, an invasive disease of the human colon, is present worldwide. It is of particular concern in tropical regions, especially in overcrowded areas of the developing world, where Shigella flexneri causes the endemic form of the disease and Shigella dyseriteriae 1 devastating epidemics. Children are the most common victims of this disease which is principally transmitted by the fecal-oral route in areas having inadequate hygiene and sanitation.


HeLa Cell Listeria Monocytogenes Shiga Toxin Shigella Flexneri Shigella Dysenteriae 
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© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • P. J. Sansonetti
    • 1
  1. 1.Unité de Pathogénie Microbienne Moléculaire, INSERM U199Institut PasteurParis Cédex 15France

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