1H NMR Spectroscopy and Spectroscopic Imaging of The Human Brain

  • Jan A. den Hollander
  • Peter R. Luyten
  • Ad J. H. Mariën
Part of the NMR Basic Principles and Progress book series (NMR, volume 27)

Abstract

The first high field 1H NMR spectroscopy studies of the animal brain were performed in 1983 [1]. These studies showed that 1H NMR spectroscopy allows in vivo observation of a number of brain compounds, including different aminoacids, creatine, choline residues, and—under certain perturbations—of lactate. Those initial studies have given rise to a large number of studies which apply 1H NMR spectroscopy to different aspects of brain metabolism, under different kind of perturbations [2]. These studies have shown that a wealth of information can be obtained about cerebral metabolism and physiology by 1H NMR spectroscopy of the animal brain.

Keywords

Lactate Choline Acetyl Creatine Meningioma 

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Copyright information

© Springer-Verlag, Berlin Heidelberg 1992

Authors and Affiliations

  • Jan A. den Hollander
    • 1
  • Peter R. Luyten
    • 1
  • Ad J. H. Mariën
    • 1
  1. 1.MR Physics DepartmentPhilips Medical SystemsBestThe Netherlands

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