Abstract
The organization of multicellular organisms depends on cell — cell communication. The signal molecules are often soluble components in the extracellular fluid, but also include odors and light. A large array of surface receptors is involved in the detection of these signals. Signals are then transduced across the plasma membrane so that enzymes at the inner face of the membrane are activated, producing second messengers, which by a complex network of interactions activate target proteins or genes [1].
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Abbreviations
- G-protein:
-
GTP-binding regulatory protein
- Gs :
-
G-protein stimulating adenylate cyclase
- Gi :
-
G-protein inhibiting adenylate cyclase
- InsP :
-
InsP 2, InsP 3 (etc.) myo-inositol mono-, bis-, tris- (etc.) phosphates with isomeric numbering (all D-) as appropriate
- PtdInsP 2 :
-
phosphatidylinositol bisphosphate
- GTP[γS]:
-
5′-[γ-thio]tri-phosphate
- GAP:
-
GTPase-activating factor
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Van Haastert, P.J.M., Janssens, P.M.W., Erneux, C. (1991). Sensory transduction in eukaryotes. In: Christen, P., Hofmann, E. (eds) EJB Reviews 1991. EJB Reviews 1991, vol 1991. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77200-9_2
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