Skip to main content

Hyperactivity and Semistarvation in the Rat: An Animal Model for Anorexia Nervosa

  • Chapter
Integrative Biological Psychiatry
  • 41 Accesses

Abstract

Patients with anorexia nervosa often show physical hyperactivity and in some patients hyperactivity is even the first symptom. Weight loss develops later on. Kron et at. (1978) observed hyperactivity in 25 out of 33 anorectic patients. Among physically active young women such as ballet dancers and marathon runners anorexia nervosa occurs more frequently than in sedentary, age-matched controls. Hyperactivity in anorectics is considered by many experts as just another means of losing weight. Epling and Pierce (1983) speculated on the possible causative role of hyperactivity for the development of anorexia and on its role in maintaining low body weight.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 16.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Epling WF, Pierce WD (1983) Activity-based anorexia in rats as a function of opportunity to run on an activity wheel. Nutr Behav 2: 37–49

    Google Scholar 

  • Korf J, Aghajanian GK, Roth RH (1973) Stimulation and destruction of the locus coeruleus: opposite effects on 3-methoxy-4-hydroxyphenylglycol-sulfate levels in the rat cerebral cortex. Eur J Pharmacol 21: 305–310

    Article  PubMed  CAS  Google Scholar 

  • Kron L, Katz JL, Gorzyuski G, Weiner H (1978) Hyperactivity in anorexia nervosa: a fundamental clinical feature. Compr Psychiatry 19: 433–440

    Article  PubMed  CAS  Google Scholar 

  • Pardridge WM, Oldendorff WH (1975) Kinetic analysis of blood-rain barrier transport of amino acids. Biochim Biophys Acta 401: 128–136

    Article  PubMed  CAS  Google Scholar 

  • Pirke KM, Spyra B (1982) Catecholamine turnover in the brain and the regulation of luteinizing hormone and corticosterone in starved male rats. Acta Endocrinol (Copenh) 100: 168–176

    CAS  Google Scholar 

  • Richter CP (1922) A behavioristic study on the activity of the rat. Comp Psychol Mongr 1: 1–55

    Google Scholar 

  • Routtenberg A, Kuznesof AW (1967) Self-starvation of rats living in activity wheels on a restricted feeding schedule. J Comp Physiol 64: 414–421

    CAS  Google Scholar 

  • Schweiger U, Warnhoff M, Pirke KM (1985) Brain tyrosine availability and the depression of central nervous norepinephrine turnover in acute and chronic starvation in adult male rats. Brain Res 335: 207–212

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1992 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Pirke, K.M., Broocks, A., Schweiger, U. (1992). Hyperactivity and Semistarvation in the Rat: An Animal Model for Anorexia Nervosa. In: Emrich, H.M., Wiegand, M. (eds) Integrative Biological Psychiatry. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77168-2_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-77168-2_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77170-5

  • Online ISBN: 978-3-642-77168-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics