Abstract
Patients with anorexia nervosa often show physical hyperactivity and in some patients hyperactivity is even the first symptom. Weight loss develops later on. Kron et at. (1978) observed hyperactivity in 25 out of 33 anorectic patients. Among physically active young women such as ballet dancers and marathon runners anorexia nervosa occurs more frequently than in sedentary, age-matched controls. Hyperactivity in anorectics is considered by many experts as just another means of losing weight. Epling and Pierce (1983) speculated on the possible causative role of hyperactivity for the development of anorexia and on its role in maintaining low body weight.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Epling WF, Pierce WD (1983) Activity-based anorexia in rats as a function of opportunity to run on an activity wheel. Nutr Behav 2: 37–49
Korf J, Aghajanian GK, Roth RH (1973) Stimulation and destruction of the locus coeruleus: opposite effects on 3-methoxy-4-hydroxyphenylglycol-sulfate levels in the rat cerebral cortex. Eur J Pharmacol 21: 305–310
Kron L, Katz JL, Gorzyuski G, Weiner H (1978) Hyperactivity in anorexia nervosa: a fundamental clinical feature. Compr Psychiatry 19: 433–440
Pardridge WM, Oldendorff WH (1975) Kinetic analysis of blood-rain barrier transport of amino acids. Biochim Biophys Acta 401: 128–136
Pirke KM, Spyra B (1982) Catecholamine turnover in the brain and the regulation of luteinizing hormone and corticosterone in starved male rats. Acta Endocrinol (Copenh) 100: 168–176
Richter CP (1922) A behavioristic study on the activity of the rat. Comp Psychol Mongr 1: 1–55
Routtenberg A, Kuznesof AW (1967) Self-starvation of rats living in activity wheels on a restricted feeding schedule. J Comp Physiol 64: 414–421
Schweiger U, Warnhoff M, Pirke KM (1985) Brain tyrosine availability and the depression of central nervous norepinephrine turnover in acute and chronic starvation in adult male rats. Brain Res 335: 207–212
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Pirke, K.M., Broocks, A., Schweiger, U. (1992). Hyperactivity and Semistarvation in the Rat: An Animal Model for Anorexia Nervosa. In: Emrich, H.M., Wiegand, M. (eds) Integrative Biological Psychiatry. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77168-2_10
Download citation
DOI: https://doi.org/10.1007/978-3-642-77168-2_10
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-77170-5
Online ISBN: 978-3-642-77168-2
eBook Packages: Springer Book Archive