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Wirkungsmechanismen von Antikonvulsiva

  • Chapter
Epileptische Anfälle

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Zusammenfassung

Epileptische Anfälle können grob in generalisierte und partielle Anfälle unterschieden werden. Primär generalisierte Anfälle beruhen auf einer starken Synchronisierung der neuronalen Aktivität, ohne daß die durchschnittliche Entladungstätigkeit der Zellen ansteigen muß (Kostopoulos et al. 1982). Diese starke Synchronisation macht eine normale Verarbeitung von Informationen unmöglich. Deshalb kommt es zu Bewußtseinstörungen. Aus der Aktivität kann sich u.U. ein großer Anfall entwickeln.

Die dem Artikel zugrundeliegende Forschung wurde von der Deutschen Forschungsgemeinschaft und der Sanderstiftung unterstützt. Wir danken G. Heske und M. Bullmann für die Hilfe bei den Experimenten und der Erstellung des Manuskripts.

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Authors
  1. U. Heinemann
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  2. J. Stabel
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  3. E. Ficker
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  4. C. L. Zhang
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Editor information

Editors and Affiliations

  1. Abt. Allgemeine Psychiatrie, Albert-Ludwigs-Universität Freiburg, Hauptstraße 5, W-7800, Freiburg i. Br., Bundesrepublik Deutschland

    Jörg Walden

  2. Neurologische Klinik, Heinrich-Heine-Universität Düsseldorf, Moorenstraße 5, W-4000, Düsseldorf 1, Bundesrepublik Deutschland

    Otto W. Witte

  3. Physiologisches Institut, Westf. Wilhelms-Universität Münster, Robert-Koch-Straße 27a, W-4400, Münster, Bundesrepublik Deutschland

    E.-J. Speckmann

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© 1992 Springer-Verlag Berlin Heidelberg

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Heinemann, U., Stabel, J., Ficker, E., Zhang, C.L. (1992). Wirkungsmechanismen von Antikonvulsiva. In: Walden, J., Witte, O.W., Speckmann, EJ. (eds) Epileptische Anfälle. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77136-1_2

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  • DOI: https://doi.org/10.1007/978-3-642-77136-1_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-54872-0

  • Online ISBN: 978-3-642-77136-1

  • eBook Packages: Springer Book Archive

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