In vitro correlates of the pathogenicity of a long fibre sample of amosite asbestos compared to a short fibre sample

  • Kenneth Donaldson
Conference paper


At the Institute of Occupational Medicine we have utilised two samples of amosite asbestos to study the role of fibre length in pathobiological activity. As shown in Table 1 these two samples, which differ only in length, are very different in their ability to cause tumours, fibrosis, inflammation and immunosuppression in animals exposed in vivo.


Toxicity Dust Microbe Asbestos Carcinogenicity 


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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • Kenneth Donaldson
    • 1
  1. 1.Institute of Occupational Medicine LtdEdinburghScotland

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