A Preliminary Study of Superselective Intra-arterial Cisplatin Infusion in the Treatment of Recurrent Malignant Gliomas
Over the past 10 years, there have been a few studies of intra-arterial cisplatin (DDP) administration in patients affected by recurrent malignant intracerebral tumors [2–4, 6]. While the results were encouraging, there were still appreciable instances of systemic (oculo-, otho-, nephro-), and local (CNS) toxicity. The aim of this study was to try to reduce the systemic toxicity and augment the intraneo-plastic drug delivery.
KeywordsGlioblastoma Multiforme Anaplastic Astrocytoma Malignant Brain Tumor Karnofsky Performance Score Recurrent Malignant Glioma
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