Summary
Baby aneurysms of the common carotid artery of adult rats were induced by means of the adventitial patch method [4]. The aneurysms which could be demonstrated 8 weeks later were irradiated intermittently with 12.5-W pulses of 0.05–0.1 s duration from the 1.318 Nd:YAG laser in a 0.2-mm focus. In this way, they could be caused to contract without perforation and thrombosis of the common carotid artery.
The objective of the study was to analyze histologically the structural alterations which occur after laser irradiation of the experimentally induced aneurysms. We assume that a structural alteration of the collagen fibers which we have been able to demonstrate is the cause of the contraction of the aneurysm induced by laser irradiation.
Acute and long-term preparations between 1 and 16 months were investigated histologically. In chronic preparations, a pronounced alteration of the irradiated aneurysm wall with proliferation of myointimal cells, fibrosis, and localized calcifications could be detected.
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© 1992 Springer-Verlag Berlin Heidelberg
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Ulrich, F., Dohle, S., Schober, R. (1992). Laser Irradiation of Experimental Carotid Aneurysms: Long-term Results and Histological Alterations. In: Piscol, K., Klinger, M., Brock, M. (eds) Neurosurgical Standards Cerebral Aneurysms Malignant Gliomas. Advances in Neurosurgery, vol 20. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77109-5_37
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DOI: https://doi.org/10.1007/978-3-642-77109-5_37
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-54838-6
Online ISBN: 978-3-642-77109-5
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