Abstract
Recurrent ischemic symptoms from a hemisphere where the internal carotid artery (ICA) is occluded are either embolic or hemodynamic. Distinguishing between these two etiologies is not possible on clinical grounds alone, although multiple, brief attacks including limb shaking are suggestive of hemodynamic origin (Levine et al. 1989). In particular, when the symptoms occur in relation to orthostatic changes, a clinical suspicion of an inadequate regional flow arises. Nevertheless, in most of these patients the setting of clinical symptoms alone and even when supplemented by angiography and CT will not identify the hemodynamic cases, and additional studies are needed. Measurement of CBF during CO2 inhalation (Levine et al. 1989; Norrving et al. 1982) or after intravenous administration of acetazolamide (Vorstrup et al. 1986) has been used to evaluate the cerebral vasodilatory capacity. The development of positron emission tomography has permitted concomitant measurement of CBF, oxygen extraction fraction, and cerebral metabolism for oxygen (CMRO2), which identifies critically perfused areas during baseline conditions. In addition, measurement of CBF and cerebral blood volume (CB) can be applied for this purpose (Gibbs et al. 1984).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
EC-IC Bypass Study Group (1985) Failure of extracranial-intracranial arterial bypass to reduce the risk of ischemic stroke. Results of an international randomized trial. N Engl J Med 313:1191–1200
Gibbs JM, Leenders KL, Wise RJS, Jones T (1984) Evaluation of cerebral perfusion reserve in patients with carotid artery occlusion. Lancet 1:310–314
Levine RL, Lagreze HL, Dobkin JA, Hanson JM, Satter MR, Rowe BR, Nickles RJ (1989) Cerebral vasocapacitance and TIAs. Neurology 39:25–29
Norrving B, Nilsson B, Risberg J (1982) rCBF in patients with carotid occlusion: resting and hypercapnic flow related to collateral flow pattern. Stroke 13:155–162
Powers WJ, Tempel LW, Grubb RL (1989) Influence of cerebral hemodynamics on stroke risk: one-year follow-up of 30 medically treated patients. Ann Neurol 25:325–330
Vorstrup, S, Brun B, Lassen NA (1986) Evaluation of the cerebral vasodilatory capacity by the acetazolamide test before EC-IC bypass surgery in patients with occlusion of the internal carotid artery. Stroke 17:1291–1298
Vorstrup S (1988) Tomographic cerebral blood flow measurements in patients with ischemic cerebrovascular disease and evaluation of the vasodilatory capacity by the acetazolamide test. Acta Neurol Scand [Suppl 114] 77:1–48
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer-Verlag, Berlin Heidelberg
About this paper
Cite this paper
Vorstrup, S., Schmidt, J., Waldemar, G., Haase, J., Paulson, O.B. (1992). Identification of Hemodynamic Patients for EC-IC Bypass Surgery. In: Schmiedek, P., Einhäupl, K., Kirsch, CM. (eds) Stimulated Cerebral Blood Flow. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77102-6_18
Download citation
DOI: https://doi.org/10.1007/978-3-642-77102-6_18
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-77104-0
Online ISBN: 978-3-642-77102-6
eBook Packages: Springer Book Archive