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Psychische Krankheit im Alter pp 109–118Cite as

Genetische Hypothesen über psychogeriatrische Erkrankungen

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Zusammenfassung

Ätiologie und Pathogenese der meisten psychogeriatrischen Erkrankungen sind heute noch weitgehend unklar. Vielfach lassen sich jedoch post mortem verschiedene neuropathologische und biochemische Veränderungen nachweisen. Damit scheint deren biologische Mitverursachung zumindest denkbar. Die beobachteten Veränderungen stellen jedoch einen Endzustand dar, der nur in einem Teil der Fälle Rückschlüsse auf die Ätiologie erlaubt. Oftmals handelt es sich um Sekundärphänomene von noch unbekannten Krankheitsprozessen. Das entscheidende Hindernis für die neuropathologische und biochemische Forschung bei psychiatrischen Erkrankungen besteht darin, daß das Gehirn am Lebenden nicht zugänglich ist. Tiermodelle für die meisten derartigen Erkrankungen gibt es nicht, oder sie sind — wegen beim Tier nicht vorhandener, spezifisch menschlicher Eigenschaften — nur unzureichend auf den Menschen übertragbar.

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Authors
  1. J. Körner
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  2. M. Nöthen
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  3. P. Propping
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Editors and Affiliations

  1. Psychiatrische Universitätsklinik Bonn, Sigmund-Freud-Str. 25, 5300, Bonn 1, Germany

    Hans-Jürgen Möller  & Anke Rohde  & 

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© 1993 Springer-Verlag Berlin Heidelberg

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Körner, J., Nöthen, M., Propping, P. (1993). Genetische Hypothesen über psychogeriatrische Erkrankungen. In: Möller, HJ., Rohde, A. (eds) Psychische Krankheit im Alter. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77090-6_9

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  • DOI: https://doi.org/10.1007/978-3-642-77090-6_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77091-3

  • Online ISBN: 978-3-642-77090-6

  • eBook Packages: Springer Book Archive

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