Hippocampus and Basal Ganglia Pathology in Chronic Schizophrenics. A Replication Study from a New Brain Collection

  • B. Bogerts
  • P. Falkai
  • M. Haupts
  • B. Greve
  • U. Tapernon-Franz
  • U. Heinzmann
Conference paper


In two previous papers (Bogerts 1984; Bogerts et al. 1985) we reported reduced volumes of limbic medial temporal lobe and basal ganglia structures in postmortem brains of schizophrenics belonging to the Vogt collection in Düsseldorf. A number of subsequent planimetric postmortem and MRI studies (Table 1) also reported anatomical anomalies in limbic structures of schizophrenics, whereas in two recent studies, which were based in part on very old cases (Heckers et al. 1989, 1990), no significant volume reductions of hippocampus, parahippocampal gyrus, and amygdala could be found.


Basal Ganglion Parahippocampal Gyrus Limbic Structure Neuroleptic Drug Significant Volume Reduction 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • B. Bogerts
    • 1
  • P. Falkai
  • M. Haupts
  • B. Greve
  • U. Tapernon-Franz
  • U. Heinzmann
  1. 1.Rheinische LandesklinikPsychiatrische Klinik der Heinrich-Heine Universität DüsseldorfDüsseldorf 12Germany

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