Abstract
Schizophrenics are more variable than normals on almost any psychophysiological measure (Callaway 1975). One of these variable measures is the event-related potential (ERP), which is the brain’s transient electrical response to discrete events. Previous investigations of ERP variability in schizophrenia have employed curve fitting techniques, peak picking, or principal component analysis to determine amplitude or latency variability of individual ERP components, particularly the P300 component (Michalewski 1986; Thomas et al. 1989). Such approaches are, however, made difficult by the presence of the ongoing EEC.
The financial support of the Rebecca Cooper Foundation of NSW and IBM Australia is gratefully acknowledged.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Callaway E (1975) Evoked potential variability and cognitive variability. In: Callaway E (ed) Brain electrical potentials and individual psychological differences. Grune and Stratton, New York, pp 63–79
Endicott J, Spitzer RL (1979) Use of the research diagnostic criteria and the schedule for affective disorders and schizophrenia. J Nerv Ment Dis 171:34–39
Michalewski HJ, Prasher DK, Starr A (1986) Latency variability and temporal interrelationships of the auditory event-related potentials (Nl, P2, N2, and P3) in normal subjects. Electroencephalogr Clin Neurophysiol 65:59–71
Robins LN, Wing J, Helzer J (1987) Composite International Diagnostic Interview. World Health Organization, Geneva
Thomas DG, Neer CM, Price JM (1989) Analyses of single-trial Nl amplitude and latency variability and their influence on the average evoked potential. Electroencephalogr Clin Neurophysiol 74:228–235
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1993 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Anderson, J., Rennie, C., Gordon, E., Meares, R. (1993). The Quantification of Variability in Event-Related Potentials and Its Application to Schizophrenia. In: Maurer, K. (eds) Imaging of the Brain in Psychiatry and Related Fields. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77087-6_34
Download citation
DOI: https://doi.org/10.1007/978-3-642-77087-6_34
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-77089-0
Online ISBN: 978-3-642-77087-6
eBook Packages: Springer Book Archive