Evaluation of Total Sleep Deprivation by Single Photon Emission Computerized Tomography
Total sleep deprivation (TSD) has a clear-cut positive effect on mood in depressed patients. Pflug and Tölle (1971) demonstrated that TSD can produce a dramatic effect on depressive symptoms within 24 h. Wu and Bunney (1990) pointed out that an average of 59% of patients respond to TSD as a treatment.
KeywordsNickel Depression Dementia Technetium
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- APA (American Psychiatric Association) (1987) diagnostic and statistical manual of mental disorders, DSM III-R, 3rd rev edn. APA, Washington DCGoogle Scholar
- Gillin JC, Buchsbaum MS, Dupont R, Wu J (1990) Localized cerebral metabolism in man: effects of sleep and sleep deprivation. In: Abstracts Book 10th Congress of the European Sleep Research Society, p 40Google Scholar
- Gustafson L, Risberg J, Silversskiöld P (1981) Cerebral blood flow in dementia and depression. Lancet 275Google Scholar
- Kaendler SH, Weber R, Volk S, Maul FD, Hertel A, Pflug B, Hör G (1990) Evaluation of total sleep deprivation by SPECT. In: Abstract Book 2nd International Symposium Imaging of the brain in Psychiatry and related fields p 110Google Scholar
- Schlegel S, Aldenhoff JB, Eissner D, Lindner P, Nickel O (1989) Regional cerebral blood flow in depression: associations with psychopathology. J Affective Disord: 211–218Google Scholar
- Wu J, Buchsbaum MS, Gillin JC (1988) Positron emission tomography study of sleep deprivation. Sleep Res 16:796Google Scholar