Abstract
Clinical trials to evaluate the potential of adoptive immunotherapy in cancer patients have been restricted to the use of lymphoid effector cells [1,2]. Of the other probably even more important host defense system against tumor growth, the mononuclear phagocyte system [3], only monocytes (mo) have been reinfused [4] which, however, represent immature precursor cells and acquire full functional competence only upon further maturation. This might at least in part be due to the many technical problems associated with the generation of human mature macrophages (MO).
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© 1993 Springer-Verlag Berlin Heidelberg
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Andreesen, R., Scheibenbogen, C., Brugger, W., Löhr, G.W. (1993). Adoptive Transfer of Autologous Cytotoxic Macrophages Grown from Blood Monocytes. A New Approach to Cancer Immunotherapy. In: Fleischer, J. (eds) Leukemias. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77083-8_23
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DOI: https://doi.org/10.1007/978-3-642-77083-8_23
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