Abstract
Due to the improved survival of cancer patients receiving chemo- and radiotherapy, the risk of developing a second primary tumor has become a problem in planning the management of patients with a first malignancy [3]. It has been established that up to 10% of all the acute leukemias are of therapy-induced type, i.e., arise as a consequence of the cytotoxic therapy for a tumor or immunopathological disorder [1]. It is therefore important to quantitate the degree of the carcinogenicity of such compounds, determine the range of patients most at risk of developing a secondary leukemia and outline the measures which should be made in order to minimize the carcinogenicity of various treatment modalities.
This study was supported by grants: National Scientific and Research Foundation (OTUA) 1012 and Ministry of Welfare (ETT)
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© 1993 Springer-Verlag Berlin Heidelberg
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Raposa, T., Várkonyi, J. (1993). Risk Prediction of Therapy-Induced Leukemia After Cytostatic Treatment. In: Fleischer, J. (eds) Leukemias. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77083-8_14
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DOI: https://doi.org/10.1007/978-3-642-77083-8_14
Publisher Name: Springer, Berlin, Heidelberg
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