The Effects of Complement Activation on Platelets
The platelet is a blood element essential to the maintenance of hemostasis. In order to participate in the formation of a hemostatic plug, the platelet must be able to respond to an array of biochemical signals. These signals may arise from other platelets, endothelial cells, or activated proteins of the coagulation and kininogen pathways. The platelet also exhibits physiological responses to activated proteins of another cascade pathway, complement. The interaction of blood platelets with the complement system is the subject of this review.
KeywordsComplement Activation Human Platelet Paroxysmal Nocturnal Hemoglobinuria Platelet Membrane Platelet Surface
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