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Genetic Diversity of RNA Viruses pp 143–164Cite as

Genetic Diversity and Evolution of Retroviruses

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 176))

Abstract

Retroviruses are one of the most widespread and probably the most biologically diverse group of infectious agents of vertebrates. Virtually all mammals—as well as some birds, reptiles, and fish—have yielded infectious retroviruses when examined sufficiently closely. Within a species, the viruses isolated can display considerable diversity of biological properties. For example, within the group of closely related murine leukemia viruses are found agents which differ in receptors used for infection; in mode of transmission for genetic (as endogenous germline proviruses) to horizontal and vertical (via milk or infection in utero); in pathogenicity from benign to highly virulent; and in disease spectrum from a variety of malignancies of varying latency to immunodeficiencies, anemias, neurological diseases, and others.

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  1. Tufts University School of Medicine, 136 Harrison Avenue, Boston, Massachusetts, 02111, USA

    J. M. Coffin

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  1. Department of Biology, C-016, University of California, 92093, San Diego, La Jolla, CA, USA

    John J. Holland Ph.D. (Professor of Biology and Molecular Genetics) (Professor of Biology and Molecular Genetics)

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© 1992 Springer-Verlag Berlin · Heidelberg

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Coffin, J.M. (1992). Genetic Diversity and Evolution of Retroviruses. In: Holland, J.J. (eds) Genetic Diversity of RNA Viruses. Current Topics in Microbiology and Immunology, vol 176. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77011-1_10

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  • DOI: https://doi.org/10.1007/978-3-642-77011-1_10

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