Skip to main content

Cephaelis ipecacuanha A. Richard (Brazilian Ipecac): Micropropagation and the Production of Emetine and Cephaeline

  • Chapter
Medicinal and Aromatic Plants IV

Part of the book series: Biotechnology in Agriculture and Forestry ((AGRICULTURE,volume 21))

Abstract

The genus Cephaelis (family Rubiaceae) is comprised of about 100 species and is native to the tropics of the Americas, Africa, and Asia. Its species are mostly evergreen shrubs or small trees with opposite, undivided leaves and small flowers in terminal heads with an involucre of bracts. The plant generally starts flowering in the second year from germination, and the flowers have a five-toothed calyx, a five-lobed corolla, five stamens, and a two-branched style (Fig. 1). The fruits are small, usually two-seeded, berry-like drupes and their production becomes maximum three to four years after germination (Everett 1981; Chatterjee et al. 1982).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Chatterjee SK, Nandi RP, Ghosh NC (1982) Cultivation and utilization of ipecac in West Bengal. In: Atal CK, Kapur BM (eds) Cultivation and utilization of medicinal plants. Regional Research Laboratory, CSIR, Jammu-Tawi, India, pp 295–301

    Google Scholar 

  • Everett TH (1981) Cephaelis. In: The New York Botanical Garden Illustrated Encyclopedia of Horticulture, vol. 2. Garland, New York, pp 679–680

    Google Scholar 

  • Gamborg OL, Miller RA, Ojima K (1968) Nutrient requirements of suspension culture of soybean root cells. Exp Cell Res 50: 151–158

    Article  PubMed  CAS  Google Scholar 

  • Ikeda K, Teshima D, Aoyama T, Satake M, Shimomura K (1988) Clonal propagation of Cephaelis ipecacuanha. Plant Cell Rep 7: 288–291

    Article  Google Scholar 

  • Jha S, Sahu NP, Mahato SB (1988) Production of the alkaloids emetine and cephaeline in callus cultures of Cephaelis ipecacuanha. Planta Med: 504–506

    Google Scholar 

  • Lloyd G, McCown B (1980) Commercially-feasible micropropagation of mountain laurel, Kalmia latifolia, by use of shoot-tip culture, vol. 30. In: Int. Plant Propag Soc Combd Proc for 1980, pp 421–427

    Google Scholar 

  • Murashige T, Skoog F (1962) A revised medium for rapid growth and bioassays with tabacco tissue cultures. Physiol Plant. 15: 473–497

    Article  CAS  Google Scholar 

  • Radomski JL, Hagan EC, Fuyat HN, Nelson AA (1952) The pharmacology of ipecac. J Pharmacol Exp Ther 104: 421–426

    PubMed  CAS  Google Scholar 

  • Schenk RU, Hildebrandt AC (1972) Medium and techniques for induction and growth of mono- cotyledonous and dicotyledonous plant cell cultures. Can J Bot 50: 199–204

    Article  CAS  Google Scholar 

  • Teshima D, Tsuchiya T, Aoyama T, Horioka M (1984) Quantitative determination of main emetic components (emetine and cephaeline) in ipecac. IYAKUHIN KENKYU 15: 63–71

    CAS  Google Scholar 

  • Teshima D, Ikeda K, Satake M, Aoyama T, Shimomura K (1988) Production of emetic alkaloid by in vitro culture of Cephaelis ipecacuanha A. Richard. Plant Cell Rep 7: 278–280

    Article  CAS  Google Scholar 

  • The Pharmacopoeia of Japan, 11th edn (1986) English version. The Ministry of Health and Welfare, pp 1273–1274

    Google Scholar 

  • Trease GE, Evans WC (1989) Ipecacuanha. In: Pharmacognosy 13th edn. Bailliere Tindal, London, pp 595–599

    Google Scholar 

  • Wiegrebe W, Kramer WJ, Shamma M (1984) The emetic alkaloids. J Nat Prod 47: 397–408

    Article  CAS  Google Scholar 

  • Yoshimatsu K, Shimomura K (1991a) Efficient shoot formation on internodal segments and alkaloid formation in the regenerates of Cephaelis ipecacuanha A. Richard. Plant Cell Rep 9: 567–570

    Article  CAS  Google Scholar 

  • Yoshimatsu K, Shimomura K (1991b) Emetic alkaloid formation in root culture of Cephaelis ipecacuanha. Phytochemistry 30: 505–507

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Yoshimatsu, K., Shimomura, K. (1993). Cephaelis ipecacuanha A. Richard (Brazilian Ipecac): Micropropagation and the Production of Emetine and Cephaeline. In: Bajaj, Y.P.S. (eds) Medicinal and Aromatic Plants IV. Biotechnology in Agriculture and Forestry, vol 21. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77004-3_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-77004-3_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77006-7

  • Online ISBN: 978-3-642-77004-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics