Cephaelis ipecacuanha A. Richard (Brazilian Ipecac): Micropropagation and the Production of Emetine and Cephaeline
The genus Cephaelis (family Rubiaceae) is comprised of about 100 species and is native to the tropics of the Americas, Africa, and Asia. Its species are mostly evergreen shrubs or small trees with opposite, undivided leaves and small flowers in terminal heads with an involucre of bracts. The plant generally starts flowering in the second year from germination, and the flowers have a five-toothed calyx, a five-lobed corolla, five stamens, and a two-branched style (Fig. 1). The fruits are small, usually two-seeded, berry-like drupes and their production becomes maximum three to four years after germination (Everett 1981; Chatterjee et al. 1982).
KeywordsStarch Europe Mold Hydrochloride Alkaloid
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- Chatterjee SK, Nandi RP, Ghosh NC (1982) Cultivation and utilization of ipecac in West Bengal. In: Atal CK, Kapur BM (eds) Cultivation and utilization of medicinal plants. Regional Research Laboratory, CSIR, Jammu-Tawi, India, pp 295–301Google Scholar
- Everett TH (1981) Cephaelis. In: The New York Botanical Garden Illustrated Encyclopedia of Horticulture, vol. 2. Garland, New York, pp 679–680Google Scholar
- Jha S, Sahu NP, Mahato SB (1988) Production of the alkaloids emetine and cephaeline in callus cultures of Cephaelis ipecacuanha. Planta Med: 504–506Google Scholar
- Lloyd G, McCown B (1980) Commercially-feasible micropropagation of mountain laurel, Kalmia latifolia, by use of shoot-tip culture, vol. 30. In: Int. Plant Propag Soc Combd Proc for 1980, pp 421–427Google Scholar
- Teshima D, Tsuchiya T, Aoyama T, Horioka M (1984) Quantitative determination of main emetic components (emetine and cephaeline) in ipecac. IYAKUHIN KENKYU 15: 63–71Google Scholar
- The Pharmacopoeia of Japan, 11th edn (1986) English version. The Ministry of Health and Welfare, pp 1273–1274Google Scholar
- Trease GE, Evans WC (1989) Ipecacuanha. In: Pharmacognosy 13th edn. Bailliere Tindal, London, pp 595–599Google Scholar