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Uncaria elliptica: In Vitro Culture and the Production of Epicatechin and Rutin

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Medicinal and Aromatic Plants IV

Part of the book series: Biotechnology in Agriculture and Forestry ((AGRICULTURE,volume 21))

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Abstract

At least 34 species of the genus Uncaria (tribe Cinchonea, subtribe Mitragyninae Havil, family Rubiaceae) are widely distributed in Africa, tropical America, tropical and subtropical Asia (Ridsdale 1978). About 14 species have been reported in Malaysia. Uncaria species are characterized by the presence of hooks on the nodes lying opposite leaves with interpetiolar stipules and a head-shaped inflorescence. It is a woody climber the stems of which are square-shaped, bearing ovate leaves with five to seven lateral veins. The midribs are typically pubescent with long straight hairs, although sometimes only finely pubescent with glabrous laminae.

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References

  • Balant L (1981) Clinical pharmacology of (+)-cyanidanol-3: a synopsis with emphasis on pharmacokinetics. In: Conn HO (ed) Int Worksh on (+)-Cyanidanol-3 in a disease of the liver. The Royal Society of Medicine, Int Congr Symp Ser 47. Academic Press, London, pp 4954

    Google Scholar 

  • Balz JP, Das NP (1979) Uncaria elliptica a major source of rutin. Planta Med 36: 174–177

    Article  PubMed  CAS  Google Scholar 

  • Beyl CA, Sharma GC (1983) Picloram induced somatic embryogenesis in Gasteria and Haworthis. Plant Cell Tissue Organ Cult 2: 123–132

    Article  CAS  Google Scholar 

  • Broome OC, Zimmerman H (1978) In vitro propagation of Mailing 7 apple rootstock. HortScience 15: 151–510

    Google Scholar 

  • Chang P, Koh YP, Geh SL, Soepadmo E, Goh SH, Wong AK (1989) Cardiovascular effects in the rat of dihydrocorynantheine isolated from Uncaria callophylla. J Ethnopharmacol 25: 213–218

    Article  PubMed  CAS  Google Scholar 

  • Couch JF, Naghski J, Krewson CF (1946) Buckwheat as a source of rutin. Science 103: 197–198

    Article  CAS  Google Scholar 

  • Couch JF, Naghski J, Krewson CF (1952) Rutin content of Sophora japonicao. J Am Chem Soc 74: 424–425

    Article  CAS  Google Scholar 

  • Das NP, Griffiths LA (1967) Biosynthesis of (+)-[14C]-catechin by the plant Uncaria gambir Roxb. Biochem J 105: 73–77

    PubMed  CAS  Google Scholar 

  • Frisch CH, Camper ND (1987) Effect of synthetic auxins on callus induction from tea stem tissue. Plant Cell Tissue Organ Cult 8: 207–227

    Article  CAS  Google Scholar 

  • Gabor M (ed) (1986) The pharmacology of benzopyrone derivative and related compounds. Akademiai Kiado, Budapest

    Google Scholar 

  • Goh SH, Aishah S (1985) Alkaloids of Uncaria callophylla. Phytoehemistry 24: 880–886

    Article  CAS  Google Scholar 

  • Goh SH, Soepadmo E, Chang P, Aishah S, Koh YP, Nasrulhaq A, Taylor CE, Wong AK (1986) Malaysian medicinal plants, antihypertensive principles of Uncaria callophylla. Malays J Sci 8: 109–115

    CAS  Google Scholar 

  • Goh SH, Liew SL, Soepadmo E (1988) Malaysian medicinal plants used for the treatment of hypertension. In: Seminar on Malaysian Traditional Medicine, University of Malaya, Kuala Lumpur, Malaysia, pp 503–508

    Google Scholar 

  • Griffiths JQ, Krewson CF, Naghski J (eds) (1955) Rutin and related flavonoids chemistry, pharmacology, clinical applications. Mack, Easton, Pennysylvania

    Google Scholar 

  • Hartmann HT, Kester DE (eds) (1983) Plant propagation. Principles and practices. Prentice Hall International, London

    Google Scholar 

  • Herath WHMW, Sultanbawa MUS, Wannigama GP (1978) Three new ursene carboxylic acids from Uncaria thwaitessii. Phytoehemistry 17: 1979–1982

    Article  CAS  Google Scholar 

  • Herath WHMW, Sultanbawa MUS, Wannigama GP, Cave A (1979) Alkaloidal and other constituents of Uncaria elliptica and Canthium dicoccum. Phytoehemistry 18: 1385–1387

    Article  CAS  Google Scholar 

  • Humphreys FR (1964) The occurrence and industrial production of rutin in southeastern Australia. Econ Bot 18: 195–253

    Article  CAS  Google Scholar 

  • James DJ (1983) Adventitious root formation “in vitro” in apple rootstocks (Malus pumica). I. Factors affecting the length of the auxin-sensitive phase in M.P. Physiol Plant 57: 149–153

    CAS  Google Scholar 

  • Law KH (1989) Studies on rutin and (—)-epicatechin production in Uncaria elliptica plant and tissue culture. PhD Thesis, National University of Singapore

    Google Scholar 

  • Law KH, Das NP (1986) Quantitation of rutin and (—)-epicatechin in the flower of Uncaria elliptica plant using high performance liquid chromatography. In: Kon OL, Chung MCM, Hwang PLH, Leong SF, Loke KH, Thiyagarajah P, Wong PTH (eds) Contemporary themes in biochemistry. Cambridge University Press, London, pp 378–379

    Google Scholar 

  • Law KH, Das NP (1987) Dual-wavelength absorbance ratios and spectrum scanning techniques for identification of flavonoids by HPLC. J Chromatogr 388: 225–233

    Article  CAS  Google Scholar 

  • Law KH, Das NP (1989) Growth of Uncaria elliptica callus and its (—)-epicatechin production. Phytoehemistry 28: 1099–1100

    Article  CAS  Google Scholar 

  • Law KH, Das NP (1990) Studies on the formation and growth ofUncaria elliptica tissue culture. J Nat Prod 53: 125–130

    Article  CAS  Google Scholar 

  • Mante S, Tepper HB (1983) Propagation of Musa textilis Nee plants from apical meristem slices in vitro. Plant Cell Tissue Organ Cult 2: 151–159

    Article  Google Scholar 

  • Merlini L, Mendelli R, Nasini G, Hesse M (1967) Cambirine, a new indole alkaloid from Uncaria gambier. Tetrahedron Lett 16: 1571–1574

    Article  PubMed  CAS  Google Scholar 

  • Phillipson JD, Supavita N (1981) Alkaloids ofUncaria elliptica from Thailand. J Pharm Pharmacol 33: 13 (Suppl)

    Google Scholar 

  • Phillipson JD, Supavita N (1983) Alkaloids fromUncaria species Pt. 8. Alkaloids of Uncaria elliptica. Phytoehemistry 22(8): 1809–1813

    Article  CAS  Google Scholar 

  • Phillipson JD, Hemingway SR, Ridsdale CE (1978) Alkaloids of Uncaria, Part V. Their occurrence and chemotaxonomy. J Nat Prod 41: 503–570

    CAS  Google Scholar 

  • Ridsdale CE (1978) A revision ofMitragyna and Uncaria (Rubiaceae). Blumea 24: 43–100

    Google Scholar 

  • Rodriguez R (1982) Callus initiation and root formation from in vitro culture of walnut cotyledons. Hort Science 17: 195–196

    Google Scholar 

  • Rodwell CN (1950) Rutin in twoeucalyptus. Nature 165: 773–774

    Article  PubMed  CAS  Google Scholar 

  • Rothlin E, Raymond-Hamet, A (1935) Effects of gambirine on the vegetative nerves of the uterus. C R Seances Soc Biol Fil 119: 37–40

    CAS  Google Scholar 

  • Smith DR, Thorpe TA (1975) Root initiation in cuttings of Pinus radiata. II. Growth regulator interactions. J Exp Bot 26: 193–202

    Article  CAS  Google Scholar 

  • Stafford HA, Kreitlow KS, Lester HH (1986) Comparison of proanthocyanidins and related compounds in leaves and leaf-derived cell cultures of Gingko bioloba L, Pseudotsuga menziesii Franco and Ribes sanguineum. Plant Physiol 82: 1132–1138

    Article  PubMed  CAS  Google Scholar 

  • Sweet HC, Bolton WE (1979) The surface decontamination of seeds to produce axenic seedlings. Am J Bot 66: 692–698

    Article  CAS  Google Scholar 

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© 1993 Springer-Verlag Berlin Heidelberg

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Das, N.P., Law, K.H. (1993). Uncaria elliptica: In Vitro Culture and the Production of Epicatechin and Rutin. In: Bajaj, Y.P.S. (eds) Medicinal and Aromatic Plants IV. Biotechnology in Agriculture and Forestry, vol 21. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77004-3_28

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  • DOI: https://doi.org/10.1007/978-3-642-77004-3_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77006-7

  • Online ISBN: 978-3-642-77004-3

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