Skip to main content
SpringerLink
Log in
SpringerLink
Log in

Silene alba (White Campion): In Vitro Culture and Benzylisoquinoline Alkaloids Biotransformation

  • Chapter
Medicinal and Aromatic Plants IV

Part of the book series: Biotechnology in Agriculture and Forestry ((AGRICULTURE,volume 21))

  • 372 Accesses

Abstract

Silene alba (Miller) E.H.L. Krause, also known as Lychnis dioica L. or Melandrium album (Miller) Garcke, of the family Caryophyllaceae (Fig. 1) has many common names: compagnon blanc, robinet, floquet, saponaire blanche, oeil de Dieu, bourbonnaise (in French); white campion, white bachelor’s buttons, white bottle, white cuckoo flower (in English); weipe Lichtnelke, Sommetrose, Wiederstock, Junggesellenknopfe, Je-länger-je-freundlicher (in German); fischi da fischiarelichnide, gittone bianco, erba nocca, violina di macchia (in Italian) (Bonnier 1911–1935). It is a dioecious herb of varied habit, usually growing as a weed on plowed or cultivated ground throughout the whole of Europe.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Agier C, Bister-Miel F, Guignard JL (1983) Study of the mean growth rate of Silene alba cells in suspension culture: effect of macroelement concentration in the medium. Bull Soc Bot Fr 130, Lett Bot (4–5): 291–300

    Google Scholar 

  • Agier C, Bury M, El-Ech F, Cousson-Fonfraid S, Bister-Miel F, Guignard JL, Viel C (1988) Ortho- dimethoxylation and coupled dechlorination of an aromatic nucleus: a new reaction of plant cell suspension cultures. CR Acad Sci Paris Sér III, 306: 265–269

    Google Scholar 

  • Agier C, Henry M, Bister-Miel F, Guignard JL (1982) Effect of boron on the starch catabolismi in a cell suspension of Silene alba (Miller) E.H.L. Krause, CR Acad Sci Paris, Sér III, 294: 73–76

    CAS  Google Scholar 

  • Axelrod J, Shofer R, Inscoe JK, King WM, Sjoerdsma A (1958) The fate of papaverine in man and other mammals. J Pharmacol Exp Ther 124: 9–15

    PubMed  CAS  Google Scholar 

  • Belpaire FM, Bogaert MG (1975) Metabolism of papaverine, II, Species differences. Xenobiotica 5: 421–429

    Article  PubMed  CAS  Google Scholar 

  • Bister-Miel F (1987) Biotransformation of the papaverine, isopapaverine and analogs by non-alkaloid-producing vegetal cellular suspensions. PhD Thesis, University of Paris-Sud

    Google Scholar 

  • Bister-Miel F, Agier C, Bury M, Postaire E, Guignard JL, Viel C (1986) Biotransformation of papaverine to papaveraldine by Silene alba cells. Effects of extraction techniques. Plant Med Phytothér 20: 3–7

    CAS  Google Scholar 

  • Bister-Miel F, Agier C, Bury M, Viel C, Guignard JL (1988) Comparative biotransformations of benzylisoquinolines by non-alkaloid-producing cell suspensions. Bull Soc Bot Fr 135; Lett Bot (1): 57–70

    Google Scholar 

  • Bister-Miel F, Guignard JL, Bury M, Agier C (1985) Compensatory glutamine effects on in vitro plant cell growth with phosphorus deficiency. Bull Soc Bot Fr 132; Lett Bot (1): 5–14

    Google Scholar 

  • Bonnier G (1911–1935) Flore complète de France, Suisse et Belgique, vol 2. Librairie Générale de l’Enseignement, E Orlhac, Paris, p 39 and pl 78

    Google Scholar 

  • Bonnier G, Douin R (1990) La grande flore en couleurs de Gaston Bonnier, Vol 1. Berlin, Paris, 78

    Google Scholar 

  • Bouvier P, Branceni D, Prouteau M, Prudhommeaux E, Viel C (1976) Synthesis, pharmacological and conformational study of 4-benzyl isoquinoline analogs of papaverine. Eur J Med Chem 11: 271–278

    CAS  Google Scholar 

  • Brassart C, Dubois J, Bouriquet R (1977) Carbohydrate nutrition of a cell suspension of Silene alba (Miller) E.H.L. Krause. CR Acad Sci Paris Sér D 285: 759–762

    CAS  Google Scholar 

  • Brassart C, Dubois J, Bouriquet R (1977) Nitrogen nutrition of Silene cells in suspension culture (Silene alba) Miller E.H.L. Krause). CR Acad Sci Paris Sér D 287: 1373–1376

    Google Scholar 

  • Brassart C, Dubois J, Bouriquet R (1982) Effects of gibberellic acid on the growth of Silene alba. Bull Soc Bot Fr 129; Lett Bot (4–5): 259–269

    Google Scholar 

  • Brassart C, Eb P, Plichon B, Dubois J (1976) Use of antibiotics in cell cultures of Silene in the fermentor. CR Congr Nati Soc Savantes, Sect Sci 101: 455–463

    CAS  Google Scholar 

  • Brassart C, Rambour S, Bouriquet R (1984) Glutamate dehydrogenase and glutamine synthetase activities in a cellular suspension of Silene alba grown in the presence of various nitrogen sources. Physiol Veg 22: 801–809

    CAS  Google Scholar 

  • Christinaki H, Bister-Miel F, Hammoumi H, Bury M, Guignard JL, Viel C (1987) Biotransformation of isopapaverine by Silene alba cell suspensions. Phytochemistry 26: 2991–2994

    Article  CAS  Google Scholar 

  • Cronquist A (1981) An integrated system of classification of flowering plants. Columbia Univ Press, New York

    Google Scholar 

  • Dorisse P, Gleye J, Loiseau P, Puig P, Edy AM, Henry M (1988) Comparison between two plant cell suspensions towards papaverine biotransformation. J Nat Prod (Lloydia) 51: 532–536

    Article  CAS  Google Scholar 

  • Dubois J (1975) Quantitative analysis of growth in a batch culture of Silene alba (Miller) E.H.L Krause. Bull Soc Bot Fr 122: 269–279

    CAS  Google Scholar 

  • Dubois J, Rambour S, Vasseur J (1976) Growth of a cellular suspension ofSilene alba (Miller) E.H.L. Krause and the variation of nucleic acids. CR Congr Natl Soc Savantes, Sect Sci 101: 441–454

    CAS  Google Scholar 

  • Garner RC (1976) The role of epoxides in bioactivation and carcinogenesis. In: Bridges JW, Chasseaud LF (eds) Progress in drug metabolism, Vol 1. John Wiley, London, pp 77–128 (see pp 83–87)

    Google Scholar 

  • Henry M, Benois M, Ly Thi B, Guignard JL (1978) The effect of naphtoxyacetic acid (NOA) on the growth of Silene alba (Miller) E.H.L. Krause cellular suspensions. Bull Soc Bot 125: 5–16

    CAS  Google Scholar 

  • Hutchinson J (1973) The families of flowering plants. Clarendon Press, Oxford

    Google Scholar 

  • Legrand B, Dubois J (1977) Development of peroxidases and auxin oxidases during the growth cycle of a Silene alba (Miller) suspension culture. CR Acad Sci Paris Sér D 285: 661–666

    CAS  Google Scholar 

  • Legrand B, Dubois J (1978) Effect of growth regulators on proliferation, peroxidase activity and isoperoxidase in cell suspension of Silene alba. Biol Plant 20: 107–113

    Article  CAS  Google Scholar 

  • Lejay P, Viel C, Uchida-Ernouf G (1977) New analogs of papaverine: synthesis, pharmacological and conformational study of 4-benzylisoquinolines substituted in the 1 or 3 position. Farm Ed Sci 32: 3–24

    CAS  Google Scholar 

  • Marie-Alsabek F, Morvan H, Dubois J, Bouriquet R (1984) Effect of pectic acid polymers released during plant cell culture on the growth of cell suspension cultures of Silene. CR Acad Sci Paris Ser III, 298: 301–304

    Google Scholar 

  • Morvan C, Priem B, Verdus MC, Kwan JS, Morvan C (1987) Relationship between the acidity of the pectic acid polymers from suspension cultured cells of white campion and their promoting effects on the growth. Food Hydrocol 1: 501–503

    Article  CAS  Google Scholar 

  • Morvan C, Verdus MC, Feghali R, Morvan H (1987) Influence of culture age and calcium deficiency on the physicochemical properties and ultrastructural aspects of the cell wall of suspension cultured cells of whiteSilene. Bull Soc Bot Fr 134, Lett Bot (4–5): 323–336

    Google Scholar 

  • Murashige T, Skoog F (1962) A revised medium for rapid growth and bioassays with tobacco tissue culture. Physiol Plant 15: 473–497

    Article  CAS  Google Scholar 

  • Nitsch JP, Nitsch C (1956) Auxin-dependent growth of excisedHelianthus tuberosus tissues. Am J Bot 43: 839–851

    Article  CAS  Google Scholar 

  • Poulle M, Rambour S (1985) Regulation of nitrate reductase in suspension culture of Silene alba. Immuno-chemical approach. Plant Sci (Limerick, Irel) 40: 111–115

    Article  CAS  Google Scholar 

  • Prudhommeaux E, Viel C, Delbarre B (1971) Researches in isoquinoline series IX. Syntheses and properties of new 6,7-dimethoxy isoquinolines V. Benzyl derivatives substituted in position 2 or in position 4. Chim Thér 6: 358–366

    CAS  Google Scholar 

  • Rambour S, Poulle M, Deniau JL, Brassart C (1983) Regulation of nitrate reductase activity in a cell suspension culture of Silene alba. Can J Bot 61: 3523–3528

    Article  CAS  Google Scholar 

  • Rambour S, Vasseur J, Dubois J (1977) Demonstration of poly adenylic RNA in Silene alba cell suspensions. CR Acad Sci Paris Ser D 284: 1063–1066

    CAS  Google Scholar 

  • Rideau M, Morard P, Gansser C, Chenieux JC, Viel C (1988) Biotransformation and inductive behaviour of papaverine on various vegetal strains. Structure of compounds obtained. Pharmazie 43: 332–334

    CAS  Google Scholar 

  • Rosazza JP, Kammer M, Youel L, Smith RW, Erhardt PW, Truong DH, Leslie SW (1977) Microbial models of mammalian metabolism O-demethylation of papaverine. Xenobiotica 7: 133–134

    Article  PubMed  CAS  Google Scholar 

  • Servin A, Jacquot C, Lussiana JP, Viel C (1985) Metabolism of 6,7-dimethoxy 4-(para-chlorobenzyl) isoquinoline, I. Single dose pharmacokinetics in the rat and mouse. Xenobiotica 15: 553–566

    Article  PubMed  CAS  Google Scholar 

  • Tissut M, Severin F (eds) (1984) Plantes, herbicides et desherbage. Association de coordination agricole, Paris, pp 115–119

    Google Scholar 

  • Tutin TG, Heywood VH, Burges NA, Valentine DH, Walters SM, Webb DA (1964) Flora Europaea, vol 1. University Press, Cambridge

    Google Scholar 

  • Verdeil JL, Bister-Miel F, Agier C, Plat M, Guignard JL, Viel C (1985) Difference in behavior of two vegetal cellular suspensions towards papaverine biotransformation. CR Acad Sci Paris Sér III, 300: 305–308

    Google Scholar 

  • Verdeil JL, Bister-Miel F, Guignard JL, Viel C (1986) Papaverine biotransformation by Silene alba cell suspension. Planta Med 52: 1–3

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Faculty of Pharmacy, University of Tours, 2 bis boulevard Tonnellé, 37042, Tours Cedex, France

    C. Viel

  2. Faculty of Pharmacy, University of Paris-Sud, 3 rue J.B. Clément, 92296, Châtenay-Malabry Cedex, France

    F. Bister-Miel & J. L. Guignard

Authors
  1. C. Viel
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. F. Bister-Miel
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. L. Guignard
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. A-137, New Friends Colony, 110065, New Delhi, India

    Y. P. S. Bajaj

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Viel, C., Bister-Miel, F., Guignard, J.L. (1993). Silene alba (White Campion): In Vitro Culture and Benzylisoquinoline Alkaloids Biotransformation. In: Bajaj, Y.P.S. (eds) Medicinal and Aromatic Plants IV. Biotechnology in Agriculture and Forestry, vol 21. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77004-3_22

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-77004-3_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77006-7

  • Online ISBN: 978-3-642-77004-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation