Skip to main content
SpringerLink
Log in

Escherichia coli Strains in Which the Chromosome Is Replicated from Origins Other than oriC

  • Conference paper
Book cover DNA Replication: The Regulatory Mechanisms

Abstract

The Escherichia coli chromosome is bidirectionally replicated from a unique origin, oriC. Various strains exist in which chromosome replication is controlled by other replicons, located at varying distance from oriC. The copy number determined by the alternative replicon may be different from that of the wild type, replication can be bidirectional or show varying degrees of unidirectionality, and initiation is usually randomly timed during the cell cycle. The more chromosome replication deviates from the normal situation with respect to the above characteristics, the more the cell cycle and growth of the strains are disturbed.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Bernander R, Dasgupta S, and Nordström K (1991) The E. coli cell cycle and the plasmid R1 replication cycle in the absence of the DnaA protein. Cell 64: 1145–1153.

    Article  PubMed  CAS  Google Scholar 

  • Bernander R, Merryweather A, and Nordström K (1989) Overinitiation of replication of the Escherichia coli chromosome from an integrated runaway-replication derivative of plasmid R1. J Bacteriol 171: 674–683.

    PubMed  CAS  Google Scholar 

  • Bernander R, and Nordström K (1990) Chromosome replication does not trigger cell division in E. coli. Cell 60: 365–374.

    Article  PubMed  CAS  Google Scholar 

  • Bird RE, Chandler M, and Caro L (1976) Suppression of an Escherichia coli dnaA mutation by the integrated R factor R. 100.1: Change of chromosome replication origin in synchronized cultures. J Bacteriol 126: 1215–1223.

    PubMed  CAS  Google Scholar 

  • Brasch MA, and Meyer RJ (1988) Integrative suppression of dnaA46 by broad host-range plasmid R1162. Mol Gen Genet 215: 139–145.

    Article  PubMed  CAS  Google Scholar 

  • Brewer BJ (1988) When polymerases collide: Replication and the transcriptional organization of the E. coli chromosome. Cell 53: 679–686.

    Article  PubMed  CAS  Google Scholar 

  • Chesney RH, and Scott JR (1978) Suppression of a thermosensitive dnaA mutation of Escherichia coli by bacteriophage P1 and P7. Plasmid 1: 145–163.

    Article  PubMed  CAS  Google Scholar 

  • Dasgupta S, Bernander R, and Nordström K (1991) In vivo effect of the tus mutation on cell division in an Escherichia coli strain where chromosome replication is under the control of plasmid R1. Res Microbiol 142: 177–180.

    Article  PubMed  CAS  Google Scholar 

  • Datta N, and Barth PT (1976) Hfr formation by I pilus-determining plasmids in Escherichia coli K-12. J Bacteriol 125: 811–817.

    PubMed  CAS  Google Scholar 

  • de Massy B, Fayet O, and Kogoma T (1984) Multiple origin usage for DNA replication in sdrA(rnh) mutants of Escherichia coli K-12. Initiation in the absence of oriC. J Mol Biol 178: 227–236.

    Article  PubMed  Google Scholar 

  • Diaz R, and Pritchard RH (1978) Cloning of replication origins from the E. coli K12 chromosome. Nature 275: 561–564.

    Article  PubMed  CAS  Google Scholar 

  • Donachie WD (1968) Relationship between cell size and time of initiation of DNA replication. Nature 219: 1077–1079.

    Article  PubMed  CAS  Google Scholar 

  • François V, Conter A, and Louarn J-M (1990) Properties of new Escherichia coli Hfr strains constructed by integration of pSC101-derived conjugative plasmids. J Bacteriol 172: 1436–1440.

    PubMed  Google Scholar 

  • Froehlich BJ, Tatti K, and Scott JR (1983) Evidence for positive regulation of plasmid prophage P1 replication: Integrative suppression by copy mutants. J Bacteriol 156: 205–211.

    PubMed  CAS  Google Scholar 

  • Kogoma T (1986) RNase H-defective mutants of Escherichia coli. J Bacteriol 166: 361–363.

    PubMed  CAS  Google Scholar 

  • Koppes L, and Nordström K (1986) Insertion of an R1 plasmid into the origin of replication of the E. coli chromosome: Random timing of replication of the hybrid chromosome. Cell 44: 117–124.

    Article  PubMed  CAS  Google Scholar 

  • Kuempel PL, Duerr SA, and Maglothin PD (1978) Chromosome replication in an Escherichia coli dnaA mutant integratively suppressed by prophage P2. J Bacteriol 134: 902–912.

    PubMed  CAS  Google Scholar 

  • Kuempel PL, Duerr SA, and Seeley NR (1977) Terminus region of the chromosome in Escherichia coli inhibits replication forks. Proc Natl Acad Sci USA 74: 3927–3931.

    Article  PubMed  CAS  Google Scholar 

  • Lindahl G, Hirota Y, and Jacob F (1971) On the process of cellular division in Escherichia coli: Replication of the bacterial chromosome under control of prophage P2. Proc Natl Acad Sci USA 68: 2407–2411.

    Article  PubMed  CAS  Google Scholar 

  • Louarn J, Patte J, and Louarn J-M (1982) Suppression of Escherichia coli dnaA46 mutations by integration of plasmid R100.1 derivatives: Constraints imposed by the replication terminus. J Bacteriol 151: 657–667.

    PubMed  CAS  Google Scholar 

  • Mao Y-M, Shi Q, Li Q-G, and Sheng Z-J (1991) recA gene dependence of replication of the Escherichia coli chromosome initiated by plasmid pUC13 integrated at predetermined sites. Mol Gen Genet 225: 234–240.

    Article  PubMed  CAS  Google Scholar 

  • Martin RR, Thorlton CL, and Unger L (1981) Formation of Escherichia coli Hfr strains by integrative suppression with the P group plasmid RP1. J Bacteriol 145: 713–721.

    PubMed  CAS  Google Scholar 

  • Moody EEM, and Runge R (1972) The integration of autonomous transmissible plasmids into the chromosome of Escherichia coli K12. Genet Res 19: 181–186.

    Article  PubMed  CAS  Google Scholar 

  • Neidhardt FC, Ingraham JL, Brooks Low K, Magasanik B, Schaechter M, and Umbarger HE (eds.) (1987) Escherichia coli and Salmonella typhimurium: Cellular and molecular biology. (Washington, DC: American Society for Microbiology) Chapters 65–67.

    Google Scholar 

  • Nishimura Y, Caro L, Berg CM, and Hirota Y (1971) Chromosome replication in Escherichia coli IV. Control of chromosome replication and cell division by an integrated episome. J Mol Biol 55: 441–456.

    Article  PubMed  CAS  Google Scholar 

  • Nishimura A, Nishimura Y, and Caro L (1973) Isolation of Hfr strains from R+ and ColV2+ strains of Escherichia coli and derivation of an R’lac factor by transduction. J Bacteriol 116: 1107–1112.

    PubMed  CAS  Google Scholar 

  • Nordström K, Bernander R, and Dasgupta S (1991) Analysis of the bacterial cell cycle using strains in which chromosome replication is controlled by plasmid Rl. Res Microbiol 142: 181–188.

    Article  PubMed  Google Scholar 

  • Skarstad K, Boye E, and Steen HB (1986) Timing of initiation of chromosome replication in individual Escherichia coli cells. EMBO J5: 1711–1717.

    Google Scholar 

  • Sotomura M, and Yoshikawa M (1975) Reinitiation of chromosome replication in the presence of chloramphenicol under an integratively suppressed state by R6K. J Bacteriol 122: 623–628.

    PubMed  CAS  Google Scholar 

  • Torrey TA, Atlung T, and Kogoma T (1984) dnaA suppressor (dasF) mutants of Escherichia coli are stable DNA replication (sdrA/rnh) mutants. Mol Gen Genet 196: 350–355.

    Article  PubMed  CAS  Google Scholar 

  • von Meyenburg K, Boye E, Skarstad K, Koppes L, and Kogoma T (1987) Mode of initiation of constitutive stable DNA replication in RNase H-defective mutants of Escherichia coli K-12. J Bacteriol 169: 2650–2658.

    Google Scholar 

  • Yamaguchi K, and Tomizawa J-I (1980) Establishment of Escherichia coli cells with an integrated high copy number plasmid. Mol Gen Genet 178: 525–533.

    Article  PubMed  CAS  Google Scholar 

  • Yoshimoto H, and Yoshikawa M (1975) Chromosome-plasmid interaction in Escherichia coli K-12 carrying a thermosensitive plasmid, Rts1, in autonomous and in integrated states. J Bacteriol 124: 661–667.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Microbiology, The Biomedical Center, University of Uppsala, Box 581, S-751 23, Uppsala, Sweden

    Rolf Bernander, Santanu Dasgupta & Kurt Nordström

Authors
  1. Rolf Bernander
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Santanu Dasgupta
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kurt Nordström
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Institut Jacques Monod, CNRS, Université Paris 7, 2 place Jussieu, 75251, Paris Cedex 05, France

    Patrick Hughes  & Masamichi Kohiyama  & 

  2. Institut für Biochemie, Karlstraße 23, 8000, München 2, Germany

    Ellen Fanning

Rights and permissions

Reprints and permissions

Copyright information

© 1992 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Bernander, R., Dasgupta, S., Nordström, K. (1992). Escherichia coli Strains in Which the Chromosome Is Replicated from Origins Other than oriC . In: Hughes, P., Fanning, E., Kohiyama, M. (eds) DNA Replication: The Regulatory Mechanisms. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76988-7_2

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-76988-7_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76990-0

  • Online ISBN: 978-3-642-76988-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation