Na,K-ATPase, Structure and Transport Mechanism

  • P. L. Jørgensen
Part of the Membrane Transport in Biology book series (MEMBRANE, volume 5)


The Na,K pump is found in the surface membrane of most animal cells. In coupling the hydrolysis of ATP to active transport of 3 Na+ out and 2 K+ into the cell, the pump is electrogenic and necessary for maintaining the membrane potential of excitable cells. Primary active Na,K pumping is a key process for the active uptake of nutrients, salts and water and the regulation of fluid and electrolyte homeostasis in mammals. The pump maintains electrochemical gradients for Na+ (ΔμNa) for utilization in carrier mediated secondary active transport processes in kidney, intestine and other epithelia.


Sarcoplasmic Reticulum Cardiac Glycoside Transmembrane Segment Adenylate Kinase Pump Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 1992

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  • P. L. Jørgensen

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