Resistance and Tolerance of Bacteria to E Colicins
It is easy to select colicin non-sensitive mutants from a population of a colicin sensitive strain. In most strains, they occur in relatively high frequencies without induction. It is also easy to exclude colicin immunity as a possible cause of non-sensitivity. However, it is not easy to distinguish between colicin resistance and colicin tolerance. In this study, experimental evidence concerning this problem is presented; we used the indicator strain Escherichia coli K12-Row and its spontaneous mutants selected for decreased sensitivity to colicins E1-E9 as a model system.
KeywordsParent Strain Inhibition Zone Resistant Mutant Tolerant Mutant Quantitative Marker
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