Introduction to the Microcin Session

  • Roberto Kolter
  • Felipe Moreno
Conference paper
Part of the NATO ASI Series book series (volume 65)


The microcins constitute a family of low-molecular-weight antibiotic substances produced by diverse strains of Enterobacteriaceae. Clinical isolates of Enterobacteriaceae have been screened for the production substances that can pass through cellophane membranes with a molecular weight cutoff of about 10,000 daltons and inhibit the growth of lawns of standard laboratory strains of Escherichia coli. Using this as an operational definition, almost twenty different microcins have been identified to date.


Clinical Isolate Operational Definition Amino Acid Peptide Molecular Weight Cutoff Production Substance 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • Roberto Kolter
    • 1
  • Felipe Moreno
    • 2
  1. 1.Department of Microbiology and Molecular GeneticsHarvard Medical SchoolBostonUSA
  2. 2.Unidad de Genética MolecularHospital Ramón y CajalMadridSpain

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