ADP-Ribosylation of Signal-Transducing Guanine Nucleotide-Binding Proteins by Pertussis Toxin

  • P. Gierschik
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 175)


The gram-negative bacterium Bordetella pertussis, the causative agent of whooping cough, produces a number of virulence factors, among which pertussis toxin is undoubtedly of major importance (Weiss and Hewlett 1986). Pertussis toxin elicits a myriad of biological effects in patients suffering from whooping cough or infected laboratory animals and has thus received several names, including histamine-sensitizing factor, lymphocytosis-promoting factor, islet-activating protein (IAP), or simply pertussigen.


Cholera Toxin Guanine Nucleotide Pertussis Toxin Pertussis Toxin Substrate Photolyzed Rhodopsin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin · Heidelberg 1992

Authors and Affiliations

  • P. Gierschik
    • 1
  1. 1.Pharmakologisches InstitutUniversität HeidelbergHeidelbergGermany

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