Abstract
The cellular elements fill the greater part of the brain and spinal cord and are separated by only narrow intercellular spaces, which are rich in ions, proteins, transmitters, and enzymes. The intercellular spaces are known as the ECS or microenvironment, the existence of which has been neglected by science for many years. Studies in the 1960s first gave rise to the conception of the ECS as a fluid with a complex structure and composition, in a space exactly circumscribed by cell membranes (Schmitt and Samson 1969), and is only in the last 10 years that the ECS has come to be recognized as a dynamically changing microenvironment for nerve cells, with a significant influence on the function of the nervous system.
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© 1992 Springer-Verlag Berlin Heidelberg
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Sykové, E. (1992). Conclusion. In: Ionic and Volume Changes in the Microenvironment of Nerve and Receptor Cells. Progress in Sensory Physiology, vol 13. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76937-5_8
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DOI: https://doi.org/10.1007/978-3-642-76937-5_8
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-76939-9
Online ISBN: 978-3-642-76937-5
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