Abstract
Many patients with acute leukemias can be brought into “complete remission” (CR) — a status in which the disease is clinically and morphologically unapparent — by intensive chemotherapy. Nevertheless, the majority ultimately relapse. A method to monitor the residual malignant cell burden would allow the early detection of imminent relapse and thus might influence therapeutic concepts by allowing a response-adapted treatment, bone marrow transplantation included.
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Wilmanns, W., Gerhartz, H.H., Schmetzer, H., Nüssler, V., Sauer, H., Clemm, C. (1992). Detection of Minimal Disease in Hematological Malignancies. In: Bannasch, P. (eds) Cancer Diagnosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76899-6_6
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DOI: https://doi.org/10.1007/978-3-642-76899-6_6
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Print ISBN: 978-3-540-54503-3
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