Esophageal Cancer: Problems and Challenges in Early Detection

  • P. B. Desai
Conference paper


Cancer of the esophagus is a distressing disease to treat as most patients present late and the overall results are poor worldwide, save a very few stray series published (Akiyama et al. 1981, Mathisen et al. 1988). There is little doubt that apart from the generally rapid spread of this cancer, due to the rich lymphatic plexus within the organ and its ramifications in the thorax, abdomen, and neck, the poor results are due to a delayed diagnosis as the disease is asymptomatic in its early stages. Results collected for early T1N0M0 cases show impressive cure rates ranging from 50% to 80% (Yamashita et al. 1972). This clearly indicates that inherently squamous cell carcinoma of the esophagus is not a biologically lethal disease and that concerted attempts to make an early diagnosis may be worthwhile in selected settings.


Esophageal Cancer Hiatus Hernia Reflux Esophagitis Brush Cytology Operative Specimen 
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  1. Akiyama H, Tsurumuru M, Kawamara T (1981) Principles of surgical treatment for carcinoma of the esophagus: analysis of lymph node involvement. Ann Surg 194: 438–446PubMedCrossRefGoogle Scholar
  2. Day NE, Munoz N (1982) Esophagus. In: Schottenfeld D, Fraumeni JF (eds) Cancer epidemiology and prevention. Saunders, Philadelphia, pp 596–623Google Scholar
  3. International Agency for Research on Cancer (1988) Cancer incidence in five continents, vol 5. IARC, LyonGoogle Scholar
  4. Kobayashi S, Kasugai T (1978) Brushing cytology for the diagnosis of gastric cancer involving the cardia of the lower esophagus. Acta Cytol 22: 155PubMedGoogle Scholar
  5. Mathisen DJ, Grillo HC, Wilkins EW et al. (1988) Transthoracic esophagectomy: a safe approach to carcinoma of the esophagus. Ann Thorac Surg 45: 137–143PubMedCrossRefGoogle Scholar
  6. Nadkarni JS, Waingankar PR (1991) Personal communicationGoogle Scholar
  7. Winawer SJ, Sherlock P, Belladona JA et al. (1975) Endoscopic brush cytology in esophageal cancer. JAMA 232: 1358PubMedCrossRefGoogle Scholar
  8. Wu YK, Huang GJ, Shao LF et al. (1982) Progress in the study and surgical treatment of cancer of the esophagus in China. J Thorac Cardiovasc Surg 84: 325PubMedGoogle Scholar
  9. Yamashita H, Okura J, Yoshioka T, Tanaka Y (1972) Pre-operative irradiation in treatment of cancer of the esophagus. Aust Radiol 16: 250CrossRefGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 1992

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  • P. B. Desai

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