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Opening of the Barrier in Cerebral Pathology

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Physiology and Pharmacology of the Blood-Brain Barrier

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 103))

Abstract

It has long been appreciated that many cerebral disorders are associated with deficits in blood-brain barrier (BBB) function and the interest in barrier pathology is as intense now as it has ever been. There are a number of reasons why this should be the case.

The author’s barrier studies were supported by the Wellcome Trust.

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Abbreviations

AD:

Alzheimer’s disease

BBB:

Blood-brain barrier

CNS:

Central nervous system

CSF:

Cerebrospinal fluid

HRP:

Horseradish peroxidase

MHC:

Major histocompatibility complex

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  1. P. J. Luthert
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  1. Physiology Group Biomedical Sciences Division King’s College London, University of London, Strand, WC2R 2LS, London, Great Britain

    Michael W. B. Bradbury M.A., D.M. (Oxon)

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Luthert, P.J. (1992). Opening of the Barrier in Cerebral Pathology. In: Bradbury, M.W.B. (eds) Physiology and Pharmacology of the Blood-Brain Barrier. Handbook of Experimental Pharmacology, vol 103. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76894-1_18

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  • DOI: https://doi.org/10.1007/978-3-642-76894-1_18

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