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In Situ Localization and Distribution Pattern of Apolipoproteins in Arterial Walls: A Comparative Study in Atherosclerosis and Renal Transplant Arteriopathy

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Recent Progress in Atherosclerosis Research

Part of the book series: Current Topics in Pathology ((CT PATHOLOGY,volume 87))

Abstract

Disorders of lipid metabolism are among the main risk factors for atherosclerosis, others being cigarette smoking, hypertension, diabetes mellitus, and age. In recent years, the impact of lipid metabolic disorders on the development of arteriosclerotic disease has been defined in greater detail by biochemical, genetic, clinical, and epidemiologic studies on the physiology and pathophysiology of lipid metabolism in general, and on the particular role of lipids and lipoproteins in atherogenesis. According to epidemiologic results, cholesterol plays a major part in this context:experimental studies of animals and clinical observations in humans have confirmed that the mere increase in cholesterol levels in the blood, i.e., without concurrent risk factors, is liable to provoke atherosclerotic changes.

This chapter is dedicated to Prof. Dr. K. M. Müller, Bochum

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  1. E. Vollmer
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  2. A. Roessner
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Editors and Affiliations

  1. Institut für Pathologie, Otto-von-Guericke-Universität, Leipziger Straße 44, 39120, Magdeburg, Germany

    A. Roessner (Professor Dr.) (Professor Dr.)

  2. Institut für experimentelle Biologie und Medizin, Pathologie, Forschungsinstitut Borstel, Parkalle 40, 23845, Borstel, Germany

    E. Vollmer (Professor Dr. Dr.) (Professor Dr. Dr.)

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Vollmer, E., Roessner, A. (1993). In Situ Localization and Distribution Pattern of Apolipoproteins in Arterial Walls: A Comparative Study in Atherosclerosis and Renal Transplant Arteriopathy. In: Roessner, A., Vollmer, E. (eds) Recent Progress in Atherosclerosis Research. Current Topics in Pathology, vol 87. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76849-1_5

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