Molecular Mechanisms in Myeloid Lineage Development
Recent work from my laboratory has described a new mechanism for controlling the expression of one hematopoietic colony-stimulating factor (CSF) receptor by the interaction of another CSF with its receptor . This type of transmodulation occurs at the level of mRNA stability and has interesting implications for hematopoietic cell development. It is particularly relevant to mechanisms that determine myeloid lineage restriction and its potential involvement in this process will be presented and analyzed.
KeywordsMixed Coloni Murine Bone Marrow Cell Granulocytic Cell Hemopoietic Precursor Cell Bipotential Progenitor Cell
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