Abstract
Recent work from my laboratory has described a new mechanism for controlling the expression of one hematopoietic colony-stimulating factor (CSF) receptor by the interaction of another CSF with its receptor [1]. This type of transmodulation occurs at the level of mRNA stability and has interesting implications for hematopoietic cell development. It is particularly relevant to mechanisms that determine myeloid lineage restriction and its potential involvement in this process will be presented and analyzed.
Supported by Public Health Service Grants (CA 20551 and CA 40987) from the USA National Institutes of Health.
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© 1992 Springer-Verlag Berlin Heidelberg
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Rohrschneider, L.R. (1992). Molecular Mechanisms in Myeloid Lineage Development. In: Neth, R., Frolova, E., Gallo, R.C., Greaves, M.F., Afanasiev, B.V., Elstner, E. (eds) Modern Trends in Human Leukemia IX. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 35. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76829-3_22
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DOI: https://doi.org/10.1007/978-3-642-76829-3_22
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