Structural Changes in Blast Cell Chromatin and DNA in Patients with Acute Leukemia After Cytosar and Irradiation Treatment
those which directly interact with DNA and change its stability and conformation and
those which indirectly influence DNA.
Cytosar (or β-cytosine arabinoside) belongs to the first class of drugs. Influence of Cytosar on DNA and RNA is not restricted only to its binding with these structures. It also makes ruptures in double helix DNA, causing cell destruction .
KeywordsEnthalpy Leukemia Calorimetry Arabinoside Micro Calorimetry
Unable to display preview. Download preview PDF.