Cytogenetic Disorders During Tumor Progression in Leukemia
The successes in studying the karyotype of malignant tumors as well as the achievements in molecular biology and molecular genetics have considerably deepened our knowledge concerning the role of chromosomal disorders in oncogenesis [1–4]. Recognition of clonal origin of leukemias  has stimulated the interest in studying the formation and development of cytogenetically marked leukemic clones during development of leukemias.
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