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Viral Hepatitis B and D

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Hepatobiliary Diseases

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Abstract

Although mankind has suffered the ravages of hepatitis from biblical times, it is only in the past three decades that we have begun to understand the nature of the viruses which infect the liver. We can now confidently talk of at least five viruses designated as hepatitis viruses (А, B, С or post-transfusion non-A non-B, D or delta, and E or water-borne epidemic non-A non-B). All cause acute hepatitis. Clinical manifestations alone are insufficient to allow distinction of one virus from another. However, an understanding of the biology and epidemiology of hepatitis viruses has greatly facilitated diagnosis. Hepatitis D virus (HDV) is unique because it is defective and requires hepatitis B virus (HBV) to survive. Both HBV and HDV (as well as HCV) can persist long-term and cause chronic hepatitis, cirrhosis, and/or death. Therefore, recognition of the onset and resolution of HBV or HDV infection are equally important. Moreover, highly effective vaccines against HBV have been developed and means are at hand to prevent HBV altogether and consequently, HDV.

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Suggested Reading

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Authors
  1. S. Gupta
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  2. D. A. Shafritz
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Editors and Affiliations

  1. Department of Medicine and Liver Unit, Clinica Universitaria and School of Medicine University of Navarra, Pamplona, Spain

    Jesús Prieto M.D. (Professor of Medicine) (Professor of Medicine)

  2. Liver Unit, Hospital Clinic i Provincial, University of Barcelona, Barcelona, Spain

    Joan Rodés M.D. (Professor of Medicine) (Professor of Medicine)

  3. Liver Research Center, Albert Einstein College of Medicine, Bronx, NY, USA

    David A. Shafritz M.D. (Professor of Medicine and Cell Biology and Director Marion Bessin) (Professor of Medicine and Cell Biology and Director Marion Bessin)

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© 1992 Springer-Verlag Berlin Heidelberg

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Gupta, S., Shafritz, D.A. (1992). Viral Hepatitis B and D. In: Prieto, J., Rodés, J., Shafritz, D.A. (eds) Hepatobiliary Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76802-6_14

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  • DOI: https://doi.org/10.1007/978-3-642-76802-6_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76804-0

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