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The Role of Interferon in the Management of Low-Grade Lymphoma

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Interferons: Mechanisms of Action and Role in Cancer Therapy

Part of the book series: ESO Monographs ((ESO MONOGRAPHS))

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Abstract

With the publication of Hans Strander’s work on the use of interferon as adjuvant therapy following surgery for osteogenic sarcoma [1], attention focused on the potential role of interferon in the treatment of malignant disease. Disappointingly, it soon became clear that in the majority of common cancers, interferon is ineffectual. However, with regard to haematological malignancy, it was subsequently shown to be active in hairy-cell leukaemia [2-5], the myeloproliferative disorders chronic myeloid leukaemia [6,7] and essential thrombocythaemia [8], myeloma [9] and low-grade lymphoma [10–17].

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© 1991 Springer-Verlag Berlin Heidelberg

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Rohatiner, A. (1991). The Role of Interferon in the Management of Low-Grade Lymphoma. In: Crowther, D. (eds) Interferons: Mechanisms of Action and Role in Cancer Therapy. ESO Monographs. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76787-6_5

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  • DOI: https://doi.org/10.1007/978-3-642-76787-6_5

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