Pathologic Evidence of Myocardial Damage Following Acute Brain Injuries
In one of the first reports, in 1969, Connor described two possibly linked myocardial lesions found in 8% and 9%, respectively, of 231 neurosurgical autopsies as “myocytolysis” and “fuchsinophilic degeneration”. These lesions were mainly found in cases with intracranial hemorrhage . Similar morphologic findings have generally been ascribed to adrenergic overstimulation due to stimuli from specific areas of the brain and nervous system . It is now clear that these two lesions are simply different chronologic aspects of one of the three main types of myocyte necrosis that are characterized by different structural, biochemical, and functional changes [3–5].
KeywordsFormalin Norepinephrine Catecholamine Cardiol Propranolol
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