Thrombolytic Treatment of Patients with Acute Ischemic Stroke

  • T. Brott
Conference paper


Acute thrombus formation or migration is the principal acute pathologic event for two-thirds or more of ischemic stroke patients angiographically studied within 6 h of symptom onset [1]. Consequently, the potential therapeutic role of thrombolytic agents for ischemic cerebral infarction has evoked considerable interest. Clinical studies have been facilitated by the ability to rapidly exclude patients with hemorrhagic stroke by computed tomography (CT), and investigators have been encouraged by the major clinical benefits demonstrated for thrombolytic therapy in treatment for another acute thrombotic disorder, acute myocardial infarction [2].


Acute Ischemic Stroke Thrombolytic Therapy Tissue Plasminogen Activator Thrombolytic Agent Acute Cerebral Infarction 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • T. Brott
    • 1
  1. 1.Department of NeurologyUniversity of Cincinnati College of MedicineCincinnatiUSA

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