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Efficiency of Multilocus Probes in Mother-Child-Putative Father Cases

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DNA — Technology and Its Forensic Application
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Abstract

A multilocus probe (MLP) is characterized by the parameters m (= mean number of bands common to two non-related persons) and n (= mean number of bands per person) (Hummel and Fukshansky, this volume). Hence, one can compare the performance of, say, two probes, one with the parameters ml and n1, the other with m2 and n2. If an MLP is used in a case of disputed paternity, its exclusion chance is of practical importance. The larger it is, the better the probe as a source of negative, but also of positive evidence. We regard the bands of a MLP as phenotypes of diallelic, mutually independent systems. Each system has two alleles *A and *nonA with two phenotypes

$$ \begin{gathered} + = *\text{A*A}\;\text{or *nonA*A,} \hfill \\ - = *\text{nonA*nonA}\text{.} \hfill \\ \end{gathered} $$

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Reference

  1. Honma M, Ishiyama I (1989) Probability of paternity in paternity testing using the DNA fingerprinting procedure. Hum Hered 39:165–169

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© 1991 Springer-Verlag Berlin Heidelberg

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Fukshansky, N., Hummel, K. (1991). Efficiency of Multilocus Probes in Mother-Child-Putative Father Cases. In: Berghaus, G., Brinkmann, B., Rittner, C., Staak, M. (eds) DNA — Technology and Its Forensic Application. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76632-9_31

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  • DOI: https://doi.org/10.1007/978-3-642-76632-9_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-54035-9

  • Online ISBN: 978-3-642-76632-9

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