Abstract
DNA-fingerprinting is a powerful tool for testing consanguinity in complete trios, as well as in deficiency cases. Restriction fragment length polymorphism associated with interspersed simple repetitive DNA sequences arise from different DNA fragment length that contain variable number of the repeated motifes [3]. These hypervariable simple repeat fragments are stably inherited in Mendelian fashion with an exactly defined mutation rate for (GTG)5/(CAC)5 [4]. The simple repetitive probe (GTG)5/(CAC)5 produces a highly informative band pattern in the range from 3.0 to 23.1 kilobases and if discriminates theoretically between all persons on earth, except for monozygotic twins [5, 6].
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© 1991 Springer-Verlag Berlin Heidelberg
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Pöche, H., Wrobel, G., Schneider, V., Epplen, J.T. (1991). The Identification of a Charred Body by Oligonucleotide Fingerprinting with the (GTG)5 Probe. In: Berghaus, G., Brinkmann, B., Rittner, C., Staak, M. (eds) DNA — Technology and Its Forensic Application. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76632-9_28
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DOI: https://doi.org/10.1007/978-3-642-76632-9_28
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