Platelet Transfusion in Patients with Bone Marrow Aplasia
Thrombocytopenia and the necessity of platelet transfusions for prevention of hemorrhagic complications present major problems in the management of patients with bone marrow aplasia (e.g., during multiple chemotherapy or bone marrow transplantation). The avoidance of HLA immunization with possibly resulting platelet transfusion refractoriness is of particular importance. We report the results of our transfusion strategy in patients with bone marrow aplasia with special respect to this problem.
KeywordsAcute Leukemia Platelet Transfusion Platelet Concentrate Transfusion Strategy Bone Marrow Aplasia
- 1.Gmur J, Felten A von, Osterwalder B, Honegger H, Hormann A, Sauter C, Deubelbeiss K, Berchtold W, Metaxas M, Scali G, Frick PG (1983) Delayed alloimmunization using random single donor platelet transfusions: a prospective study in thrombocytopenic patients with acute leukemia. Blood 62: 473–479PubMedGoogle Scholar