Skip to main content

Rückenmarksnahe Analgesie bei Tumorschmerz

  • Conference paper
  • 16 Accesses

Zusammenfassung

Mit der Entdeckung von Opiatangriffspunkten im Zentralnervensystem (Pert u. Snyder 1973; Terenius 1973; Simon et al. 1973) und der zu diesen Rezeptoren gehörigen endogenen Transmitter, genannt Endorphine (Hughes et al. 1975), begann eine neue Ära der Opioidforschung, die innerhalb weniger Jahre zu einer explosionsartigen Vermehrung unseres Wissensstandes hinsichtlich dieser Substanzgruppe geführt und eine Reihe von neuen praktischen Ansätzen mit sich gebracht hat, zu denen auch die hier beschriebene Methode der rückenmarksnahen Analgesie gehört.

Geschichte der rückenmarksnahen Analgesie

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Ansuategui M (1983) Cuadro de meningitis en un paciente tradado con morfina epidural. Rev Espan Anesth 30:60–61

    Google Scholar 

  • Behar M, Olshwang D, Magora F, Davidson JT (1979) Epidural morphine in treatment of pain. Lancet 1:527–529

    Article  PubMed  CAS  Google Scholar 

  • Blackshear PJ, Dorman FD, Blackshear PL, Varco RL, Buchwald H (1970) A permanently implantable self-recycling low flow constant rate multipurpose infusion pump of simple design. Surg Forum 21:136

    PubMed  CAS  Google Scholar 

  • Blackshear PJ, Rhode TD, Varco RL, Buchwald H (1975) One year of continuous heparinization in a dog using a totally implantable infusion pump. Surg Gynecol Obstet 141:176–186

    PubMed  CAS  Google Scholar 

  • Coombs DW, Saunders RL, Gaylor MS, Pageau MG (1982) Epidural narcotic infusion reservoir: implantation technique and efficacy. Anesthesiology 56:469–473

    Article  PubMed  CAS  Google Scholar 

  • Ehring E, Boeksteger A (1986) Morphologisch-histologische Veränderungen durch kontinuierliche Periduralanalgesie bei einem Karzinompatienten. Reg Anaesth 9:46–48

    PubMed  CAS  Google Scholar 

  • Hughes J, Smith TW, Kosterlitz HW, Fothergill LA, Morgan BA, Morris HR (1975) Identification of two related pentapeptides from the brain with potent opiate agonist activity. Nature 258:577–579

    Article  PubMed  CAS  Google Scholar 

  • La Motte C, Pert CB, Snyder SH (1976) Opiate receptor binding in primate spinal cord. Brain Res 112:407–412

    Article  Google Scholar 

  • Leavens M, Stratton-Hill C, Cech D, Weyland J, Weston J (1982) Intrathecal and intraventricular morphine for pain in cancer patients. J Neurosurg 56:241–245

    Article  PubMed  CAS  Google Scholar 

  • Müller H, Zierski J (1988) The Huber needle as a special canula for puncture of implanted ports and pumps - an error in many variations. Klin Wochenschr 66:963–969

    Article  PubMed  Google Scholar 

  • Müller H, Vogelsberger W, Aigner K, Herget HF, Hempelmann G (1983) Kontinuierliche peridurale Opiatapplikation mit einer implantierten Pumpe. Reg Anaesth 6:47–51

    PubMed  Google Scholar 

  • Müller H, Aigner K, Worm I, Lobisch M, Brähler A, Hempelmann G (1984) Langzeit-Erfahrungen mit der kontinuierlichen periduralen Opiatanalgesie mittels implantierter Pumpen. Anaesthesist 33:433–439

    PubMed  Google Scholar 

  • Müller H, Gips H, Krumholz W, Zierski J, Lüben V, Hempelmann G (1986) Pharmakokinetik der kontinuierlichen periduralen Morphininfusion. Anaesthesist 35:672–678

    PubMed  Google Scholar 

  • Müller H, Schnorr C, Zierski J, Hempelmann G (1988) Rückenmarksnahe Medikamenteninfusion bei Schmerzen durch maligne Tumoren oder Spastizität. Med Welt 39:829–834

    Google Scholar 

  • Niederhuber JE, Ensminger W, Gyves JW, Liepman M, Doan K (1982) Totally implanted venous and arterial access system to replace external catheters in cancer treatment. Surgery 92:706–712

    PubMed  CAS  Google Scholar 

  • Nurchi G (1984) Use of intraventricular and intrathecal morphine in intractable pain associated with cancer. Neurosurgery 15:801–803

    Article  PubMed  CAS  Google Scholar 

  • Onofrio BM, Yaksh TL, Arnold PG (1981) Continuous low-dose intrathecal morphine administration in the treatment of chronic pain of malignant origin. Mayo Clin Proc 56:516–520

    PubMed  CAS  Google Scholar 

  • Pert CB, Snyder SH (1973) Opiate receptor: demonstration in nervous tissue. Science 179:1011–1014

    Article  PubMed  CAS  Google Scholar 

  • Rhode TD, Blackshear PJ, Varco RL, Buchwald H (1977) Protracted parenteral drug infusion in ambulatory subjects using an implantable infusion pump. Trans Am Soc Artif Organs 23:13–16

    Google Scholar 

  • Rodin BA, Cohen FL, Bean WL, Martyak SN (1985) Fibrous mass complication epidural morphine administration in the treatment of chronic pain of malignant origin. Neurosurgery 16:68–70

    Article  Google Scholar 

  • Siegfried J, Lazorthes Y (1985) La neurochirurgie functioneile de l’infirmite motrice d’origin cerebrale. Neurochirurgie [Supp] 1 31:1–118

    Google Scholar 

  • Simon EJ, Hiller JM, Edelman I (1973) Sterospecific binding of the potent narcotic analgesic 3H-etorphine to rat-brain homogenate. Proc Natl Acad Sci USA 70:1947–1949

    Article  PubMed  CAS  Google Scholar 

  • Terenius L (1973) Sterospecific interaction between narcotic analgesics and a synaptic plasma membrane fraction of rat cerebral cortex. Acta Pharmacol Toxicol 32:317–320

    Article  CAS  Google Scholar 

  • Wang JK, Nauss LA, Thomas JE (1979) Pain relief by intrathecally applied morphine in man. Anesthesiology 50:149–150

    Article  PubMed  CAS  Google Scholar 

  • Yaksh TL (1981) Spinal opiate analgesia: characteristics and principles of action. Pain 11:293–346

    Article  PubMed  CAS  Google Scholar 

  • Yaksh TL, Müller H (1982) Spinal opiate analgesia. Experimental and clinical studies. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Yaksh TL, Rudy TA (1976) Analgesia mediated by a direct spinal action of narcotics. Science 192:1357–1358

    Article  PubMed  CAS  Google Scholar 

  • Zenz M, Piepenbrock S, Hüsch M, Schappler-Scheele, Neuhaus R (1981) Erfahrungen mit längerliegenden Periduralkathetern - Peridurale Morphinanalgesie bei Karzinompatienten. Reg Anaesth 4:26–30

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Müller, H., Zierski, J. (1991). Rückenmarksnahe Analgesie bei Tumorschmerz. In: von Matthiessen, H. (eds) Praktische Schmerztherapie in der Onkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76536-0_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-76536-0_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-53878-3

  • Online ISBN: 978-3-642-76536-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics