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Osteopetrosis Induced by Retrovirus, Mouse

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Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

Abstract

Retrovirus-induced osteopetrosis is not conspicuous macroscopically, appearing in the radiograph in the form of a loss of spongious structure in the vertebrae and/or a loss of the marrow cavity in other bones resulting from a thickening of the cortex (Figs. 370, 371). It is preferentially located in the iliac crest, the lower part of the vertebral column, the distal femur, and the proximal tibia, but may appear in all bones apart from the distal caudal vertebrae, particularly in cases with severe lesions. In ribs and small bones the ends are also the most commonly affected site.

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© 1991 Springer-Verlag Berlin Heidelberg

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Murray, A.B., Schmidt, J., Luz, A. (1991). Osteopetrosis Induced by Retrovirus, Mouse. In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Cardiovascular and Musculoskeletal Systems. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76533-9_44

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  • DOI: https://doi.org/10.1007/978-3-642-76533-9_44

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76535-3

  • Online ISBN: 978-3-642-76533-9

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