Polyarteritis, Rat

  • William W. Carlton
  • Jeffery A. Engelhardt
Part of the Monographs on Pathology of Laboratory Animals book series (LABORATORY)


The lesions may be recognized grossly in large and medium-sized arteries such as the mesenteric, pancreatic, hepatic, spermatic, uterine, ovarian, cerebral, and adrenal arteries (Yang 1965; Wilens and Sproul 1938; Skold 1961). The mesenteric arterties are frequently involved and are seen as segmentally thickened, tortuous, and nodular vessels often discolored by congestion and hemorrhage. The nodular appearance along the course of the vessels (usually 2—4 mm in diameter) may be seen by close inspection to be the result of thickening of the wall and aneurysmal dilatation, somtimes occluded by thrombi (Fig. 68). These lesions are increased in number in the part of the mesenteric artery nearest to the intestine. Occasionally an artery is occluded and dilated along much of its course. This can also result in infarction of the intestinal wall. Affected arteries are less readily seen grossly in sites other than the mesentery unless infarction and hemorrhage makes the lesion obvious.


Polyarteritis Nodosa Arterial Lesion Fibrinoid Necrosis Equine Viral Arteritis Splanchnic Artery 
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© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • William W. Carlton
  • Jeffery A. Engelhardt

There are no affiliations available

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