Zusammenfassung
In ihrem gleichzeitig nachdenklichen wie ironischen Editorial einer psycho-pharmakologischen Zeitschrift schlagen Shader u. Greenblatt (1982) die Bezeichnung „mind sweeper“ für den psychopharmakologisch ausgebildeten Psychiater vor. Die Autoren deuten am Beispiel einer — in diesem Fall erfolgreichen — medikamentösen Intervention in der Therapie einer (u. a.) eßgestörten Patientin die vielschichtige Problematik an, die im Mit- oder Nebeneinander von Patient, Psychopharmakologen und Psychotherapeuten entstehen kann. Im Mittelpunkt stehen dabei nicht nur diagnostische Schwierigkeiten, beispielsweise die Frage, wie häufig einer Eßstörung eine Angsterkrankung oder eine affektive Psychose zugrunde liegt (Shader u. Greenblatt 1982). Es geht dabei vielmehr auch um andere Phänomene und Gesichtspunkte, die, auch wenn sie nur zurückhaltend diskutiert werden, wahrscheinlich von mindestens gleicher Relevanz sind. An dieser Stelle sollen sie nur schlagwortartig als „berufspolitische Konkurrenz“ sowie mit den aus der Psychotherapie bekannten Begriffen „Widerstand“ und „Agieren“ skizziert werden. Dieses Spannungsfeld bildet den Rahmen für alle Überlegungen zum Verhältnis zwischen Psycho- und Pharmakotherapie, und damit auch für diese Arbeit zur Pharmakotherapie der Bulimia nervosa (B. n.).
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Literatur
Agras W, Dorian B, Kirkley B, Arnow B, Bachman J (1987) Imipramin in the treatment of bulimia: a double-blind controlled study. Int J Eating Disord 6:29–38.
American Psychiatric Association (1980) Diagnostic and statistical manual of mental disorders (DSM III), 3rd edn. APA, Washington, DC.
American Psychiatric Association (1987) Diagnostic and statistical manual of mental disorders, (DSM-III-R) 3rd edn. APA, Washington, DC.
Barlow J, Blovin J, Blovin A, Perez E (1988) Treatment of bulimia with desipramine: a double-blind crossover study. Can J Psychiatry 33:129–133.
Berger M, Pirke KM, Doerr P, Krieg C, von Zerssen D (1983) Influence of weight loss on the dexamethason suppression test. Arch Gen Psychiatry 40:585–586.
Bondy B, Ackenheil M, Müller-Spahn F, Hippius H (1988) Biologische Marker endogener Psychosen. Nervenarzt 59:565–572.
Brotman AW, Herzog DB, Woods SW (1984) Antidepressant treatment of bulimia: the relationship between bingeing and depressive symptomatology. J Clin Psychiatry 45:7–9.
Caroll BJ, Feinberg N, Greden JF, Tarika J (1981) A specific laboratory test for the diagnosis of melancholia. Arch Gen Psychiatry 38:15–22.
Cole W, Lapierre YD (1986) The use of tryptophan in normal-weight bulimia. Can J Psychiatry 31:755–756.
Coppen A (1967) The biochemistry of affective disorders. Br J Psychiatry 113:1237–1243.
Damlouji NF, Ferguson JM (1984) Trazodone-induced delirium in bulimic patients. Am J Psychiatry 141:434–435.
Fairburn CG, Cooper PJ (1983) MAOIs in the treatment of bulimia (letter). Am J Psychiatry 140:949–950.
Fairburn CG, Cooper PJ (1984) The clinical features of bulimia nervosa. Br J Psychiatry 144:238–246.
Fairburn CG, Garner DM (1986) The diagnosis of bulimia nervosa. Int J Eating Disord 5:403–419.
Fichter MM, Pirke KM, Pöllinger J, Wolfram G, Brummer E (1988) Restricted caloric intake causes neuroendocrine disturbances in bulimia. In: Pirke KM, Vandereycken W, Ploog D (eds) The psychobiology of bulimia nervosa. Springer, Berlin Heidelberg New York Tokyo, pp 42–56.
Freeman CP, Hampson M (1987) Fluoxetine as a treatment for bulimia nervosa. Int J Obes [Suppl] 11:171–177.
Fullerton DT, Swift WJ, Getto CJ, Carlson J (1986) Plasma immunoreactive beta-endorphin in bulimics. Psychol Med 16:59–63.
Garfinkel PE, Garner DM (1982) Anorexia nervosa — a multidimensional perspective. Brunner & Mazel, New York.
Garfinkel PE, Garner DM (eds) (1987) The role of drug treatment for eating disorders. Brunner & Mazel, New York.
Garner DM, Garfinkel PE (eds) (1985) Handbook of psychotherapy for anorexia nervosa and bulimia. Guilford, New York.
Garner DM, Rockert W, Olmstedt MP, Johnson C, Coscina DV (1985) Psychoeducational principles in the treatment of bulimia and anorexia nervosa. In: Garner DM, Garfinkel PR (eds) Handbook of psychotherapy for anorexia nervosa and bulimia. Guilford, New York, pp 513–572.
Garner D, Garfinkel P, Irvine M (1986) Integration and sequencing of treatment approaches for eating disorders. Psychother Psychosom 46:67–75.
Glassman AH, Walsh BT (1983) Link between depression and bulimia unclear. J Clin Psychopharmacol 3:203.
Green RS, Rau JH (1974) Treatment of compulsive eating disturbances with anticonvulsant medication. Am J Psychiatry 131:428–432.
Green RS, Rau, JH (1977) The use of diphenylhydantoin in compulsive eating disorders: further studies in anorexia nervosa. In: Vigersky RA (ed) Anorexia nervosa. Raven, New York, pp 377–382.
Gwirtsman HE, Roy-Byrne P, Yager J, Gerner RH (1983) Neuroendocrine abnormalities in bulimia. Am J Psychiatry 140:559–563.
Halmi KA (1985) Classification of the eating disorders. J Psychiatr Res 19:113–119.
Hartig M (1975) Probleme und Methoden der Psychotherapieforschung. Urban & Schwarzenberg, München.
Hatsukami D, Eckert ED, Mitchell JE (1984) Affective disorder and substance abuse in women with bulimia. Psychol Med 14:701–714.
Helmchen H, Müller-Oerlinghausen B (Hrsg) (1978) Psychiatrische Therapieforschung. Springer, Berlin Heidelberg New York.
Herridge PL, Pope HG (1985) Treatment of bulimia and rapid-cycling bipolar disorder with sodium valproate. J Clin Psychopharmacol 5:229–230.
Herzog DB (1984) Are anorectic and bulimic patients depressed? Am J Psychiatry 141:1594–1597.
Hsu LKG (1984) Treatment of bulimia with lithium. Am J Psychiatry 141:1260–1262.
Hsu LKG, Clement L, Santhouse R (1987) Treatment of bulimia with lithium. Psychopharmacol Bull 23:45–48.
Hudson JI, Laffer PS, Pope HG (1982) Bulimia related to affective disorder by family history and response to the dexamethasone suppression test. Am J Psychiatry 139:685–687.
Hudson JI, Pope HG, Jonas JM, Yurgelun-Todd D (1983a) Family history study of anorexia nervosa and bulimia. Br J Psychiatry 142:133–138.
Hudson JI, Pope HG, Jonas JM, Yurgelun-Todd D (1983 b) Phenomenologic relationship of eating disorders to major affective disorder. Psychiatry Res 9:345–354.
Hudson JI, Pope HG, Jonas JM (1983 c) Hypothalamic-pituitary-adrenal-axis hyperactivity in bulimia. Psychiatry Res 8:111–117.
Hudson JI, Pope HG, Jonas JM (1984) Psychosis in anorexia nervosa and bulimia. Br J Psychiatry 145:420–423.
Hüther G, Sprotte U, Thoemke F, Neuhoff V (1983) Die Rolle aromatischer Aminosäuren bei der Regulation von Stoffwechsel und Verhalten. Funkt Biol Med 2:18–30.
Hughes PL, Wells LA, Cunningham CJ (1986 a) The dexamethasone suppression test in bulimia before and after successful treatment with desipramine. J Clin Psychiatry 47:515–517.
Hughes PL, Wells LA, Cunningham CJ, Ilstrup DM (1986 b) Treating bulimia with desipramine. Arch Gen Psychiatry 43:182–186.
Igoin-Apfelbaum L, Apfelbaum M (1987) Naltrexone and bulimic symptoms (letter). Lancet II 8567:1087–1088.
Jimmerson DC, Brandt HA, Brewerton TD (1988) Evidence for altered serotonin function in bulimia and anorexia nervosa. In: Pirke KM, Vandereycken W, Ploog D (eds) The psychobiology of bulimia nervosa. Springer, Berlin Heidelberg New York Tokyo, pp 83–89.
Jonas JM, Gold MS (1987) Treatment of antidepressant-resistant bulimia with naltrexone. Int J Psychiatry Med 16:305–309.
Jonas JM, Pope HG, Hudson JI (1983) Treatment of bulimia with monoamine oxidase inhibitors (letter). J Clin Psychopharmacol 3:59–60.
Kaplan AS, Garfinkel PE, Darby PL, Garner DM (1983) Carbamazepine in the treatment of bulimia. Am J Psychiatry 140:1225–1226.
Kennedy SH, Piran N, Garfinkel PE (1985) Monoamine oxidase inhibitor therapy for anorexia nervosa and bulimia: a preliminary trial of isocarboxazid. J Clin Psychopharmacol 5:279–285.
Kennedy S, Piran N, Garfinkel PE (1986) Isocarboxazid in the treatment of bulimia (letter). Am J Psychiatry 143:1495–1496.
Keys A, Brozek J, Henschel A, Michelsen O, Taylor H (1950) The biology of human starvation. University of Minnesota Press, Minneapolis.
Kiesler DJ (1977) Die Mythen der Psychotherapieforschung und ein Ansatz für ein neues Forschungsparadigma. In: Petermann F (Hrsg) Psychotherapieforschung. Beltz, Weinheim, S 7–50.
Kline MD, Beeber AR (1983) Weight loss and the dexamethasone suppression test. Arch Gen Psychiatry 40:1034–1035.
Laessle RG, Kittl S, Fichter MM, Wittchen HU, Pirke KM (1987 a) Major affective disorder in anorexia nervosa and bulimia. Br J Psychiatry 151:785–789.
Laessle RG, Waadt S, Schweiger U, Pirke KM (1987 b) Zur Therapierelevanz psychobiologischer Befunde bei Bulimia nervosa. Verhaltensmodifikation Verhaltensmed 8:297–313.
Laessle RG, Schweiger U, Fichter MM, Pirke KM (1988) Eating disorders and depression. In: Pirke KM, Vandereycken W, Ploog D (eds) The psychobiology of bulimia nervosa. Springer, Berlin Heidelberg New York Tokyo, pp 90–100.
Levy A, Dixon K, Stern S (1989) How are depression and bulimia related? Am J Psychiatry 146:162–169.
Lindy DC, Walsh BT, Roose SP, Gladis M, Glassman AH (1985) The dexamethasone suppression test in bulimia. Am J Psychiatry 142:1375–137
Margittai KJ, Blouvin A, Perez E (1987) A study of the drop-outs in psychopharmacological research with bulimics. Int J Psychiatry Med 16:297–304.
Meermann R, Vandereycken W (1987) Therapie der Magersucht und Bulimia nervosa. de Gruyter, Berlin.
Mitchell JE, Groat R (1984) A placebo-controlled, double-blind trial of amitriptyline in bulimia nervosa. J Clin Psychopharmacol 4:186–193.
Mitchell JE, Pyle RL, Hatsukami D, Boutacoff LI (1984) The dexamethasone suppression test in patients with bulimia. J Clin Psychiatry 45:508–511.
Mitchell JE, Laine DE, Morley JE, Levine AS (1986) Naloxone but not CCK-8 may attenuate binge-eating behavior in patients with the bulimia syndrome. Biol Psychiatry 21:1399–1406.
Mitchell JE, Pyle RL, Eckert ED, Hatsukami D, Pomeroy C (1988) Preliminary results of a comparison treatment trial of bulimia nervosa. In: Pirke KM, Vandereycken W, Ploog D (eds) The psychobiology of bulimia nervosa. Springer, Berlin Heidelberg New York Tokyo, pp 152–157.
Murphy DL, Siever LJ, Insel TR (1985) Therapeutic responses to tricyclic antidepressants and related drugs in non-affective disorder patient populations. Prog Neuro-Psychopharmacol Biol Psychiatry 9:3–13.
Nassr DG (1986) Successful treatment of bulimia with nomifensine. Am J Psychiatry 143:373–374.
Opler LA, Mickley D (1986) Alprazolam in the treatment of bulimia. J Clin Psychiatry 47:49.
O’Rourke D, Wurtman JJ, Wurtman RJ (1988) Serotonin implicated in the etiology of seasonal affective disorder with carbohydrate craving. In: Pirke KM, Vandereycken W, Ploog D (eds) The psychobiology of bulimia nervosa. Springer, Berlin Heidelberg New York Tokyo, pp 13–17.
Paul T (1987) Zur Heterogenität des Krankheitsbildes der Bulimia nervosa. Z Klin Psychol 16:99–114.
Piran N, Kennedy S, Garfinkel PE, Owens M (1985) Affective disturbance in eating disorders. J Nerv Ment Dis 173:395–400.
Pirke KM, Pahl J, Schweiger U, Warnhoff M (1985) Metabolic and endocrine indices of starvation in bulimia: a comparison with anorexia nervosa. Psychiatry Res 15:33–39.
Pirke KM, Ploog D (1987) Biology of human starvation. In: Beumont PJ, Burrows GD, Casper RC (eds) Handbook of eating disorders Part I. Elsevier, Amsterdam, pp 79–102.
Pope HG, Hudson JI (1986) Antidepressant drug therapy for bulimia: current status. J Clin Psychiatry 47:339–345.
Pope HG, Hudson JI, Jonas MJ, Yurgelun-Todd D (1983 a) Bulimia treated with imipramine: a placebo-controlled, double-blind study. Am J Psychiatry 140:554–558.
Pope HG, Hudson JI, Jonas JM (1983b) Antidepressant treatment of bulimia: preliminary experience and practical recommendations. J Clin Psychopharmacol 3:274–281.
Pope HG, Herridge PL, Hudson JI, Fontaine R (1986) Treatment on bulimia with nomifensine. Am J Psychiatry 143:371–373.
Price WA, Babai MR (1987) Antidepressant drug therapy for bulimia (letter). J Clin Psychiatry 48:385.
Robinson PH, Checkley SA, Russell GFM (1985) Suppression of eating by fenfluramine in patients with bulimia nervosa. Br J Psychiatry 146:169–176.
Roy-Byrne P, Gwirtsman H, Edelstein CK, Yager J (1983) Eating disorders and antidepressants (letter). J Clin Psychopharmacol 3:60–61.
Russell GFM (1979) Bulimia nervosa: an ominous variant of anorexia nervosa. Psychol Med 9:429–448.
Sabine EJ, Yonace A, Farrington AJ, Barrat KH (1983) Bulimia nervosa: a placebo controlled double blind therapeutic trial of mianserin. Br J Clin Pharmacol 15:S195–S202.
Schildkraut JJ (1965) The catecholamine hypothesis of affective disorders: a review of supporting evidence. Am J Psychiatry 112:509–522.
Seligman ME (1979) Erlernte Hilflosigkeit. Urban & Schwarzenberg, München.
Shader RI, Greenblatt DJ (1982) The psychiatrist as mind sweeper (edtl). J Clin Psychopharmacol 2:233–234.
Sims EA, Goldman R, Gluck C (1968) Experimental obesity in man. Transcript Assoc Am Physicians 81:153–180.
Stern SL, Dixon KN, Nemzer E, Lake MD (1984) Affective disorder in the families of women with normal-weight bulimia. Am J Psychiatry 141:1224–1227.
Stewart JW, Walsh MT, Wright L, Roose SP, Glassman AH (1984) An open trial of MAO inhibitors in bulimia. J Clin Psychiatry 45:217–219.
Swift WJ, Kalin NH, Wamboldt FS, Kaslow N (1985) Depression in bulimia at 2-to-5-year follow up. Psychiatry Res 16:111–122.
Swift WJ, Andrews D, Barklage NE (1986) The relationship between affective disorder and eating disorders: a review of the literature. Am J Psychiatry 143:290–299.
Vandereycken W (1987) Are anorexia nervosa and bulimia variants of affective disorders? Acta Psychiatr Belg 87:267–280.
Vandereycken W, Pierloot RA (1981) Ein dimensionales Modell für Eß-und Gewichtsstörungen. In: Meermann R (Hrsg) Anorexia nervosa. Enke, Stuttgart, S 69–73.
Vandereycken W, Pierloot RA (1983) The significance of subclassification in anorexia nervosa. Psychol Med 13:543–549.
Walsh BT, Stewart JW, Wright L, Harrison W, Roose SP, Glassman AH (1982) Treatment of bulimia with monoamine oxidase inhibitors. Am J Psychiatry 139:1629–1630.
Walsh BT, Stewart JW, Roose SP, Gladis M, Glassman AH (1984) Treatment of bulimia with phenelzine. A double-blind, placebo-controlled study. Arch Gen Psychiatry 41:1105–1109.
Walsh BT, Roose SP, Glassman AH, Gladis MA, Sadik C (1985 a) Bulimia and depression. Psychosom Med 47:123–131.
Walsh BT, Stewart JW, Roose SP, Gladis M, Glassman AH (1985 b) A double-lind trial of phenelzine in bulimia. J Psychiatr Res 19:485–489.
Walsh BT, Gladis M, Roose SP, Stewart JW, Glassman AH (1987) A controlled trial of phenelzine in bulimia. Psychopharmacol Bull 23:49–51.
Walsh BT, Gladis M, Roose SP, Stewart JW, Stetner F, Glassman AH (1988) Phenelzine versus placebo in 50 patients with bulimia. Arch Gen Psychiatry 45:471–475.
Weiss T, Levitz L (1976) Diphenylhydantoin treatment of bulimia (letter). Am J Psychiatry 133:1093.
Wells LA, Logan KM (1987) Pharmacologic treatment of eating disorders. Psychosom 28:470–479.
Wermuth BM, Davis KL, Hollister LE, Stunkard AJ (1977) Phenytoin treatment of binge-eating syndrome. Am J Psychiatry 134:1249–1453.
Wold P (1983) Trazodone in the treatment of bulimia (letter). J Clin Psychiatry 44:275–276.
Wurtman JJ, Wurtman RJ, Growdon JH (1981) Carbohydrate craving in obese people. Int J Eating Dis 1:2–15.
Wurtman RF, Wurtman JJ (eds) (1986) Nutrition and the brain. Raven, New York.
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Thiel, A. (1991). Pharmakotherapie der Bulimia nervosa. In: Jacobi, C., Paul, T. (eds) Bulimia und Anorexia nervosa. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76461-5_11
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