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Donor Factors Determine Cadaveric Kidney Outcome: Should We Use It to Choose Donor-Recipient Combinations?

  • W. Niebel
  • K. H. Albrecht
  • A. Gille
  • K. Wagner
  • F. W. Eigler
  • H. Grosse-Wilde
  • J. Erhard
  • A. Daul
  • T. Philipp
Conference paper

Abstract

Up to the present, the donor-recipient combinations in kidney transplantation have been optimized in most transplant centers according to the histocompatibility system only. It was assumed that the conditions of the organ donation (the circumstances of brain death, the procedure of organ harvesting and shipment) were good or excellent. Other donor criteria were not taken into account. But there are recent studies, which have found a significant influence of donor factors in determining kidney transplant survival rates at a high degree, comparable to that of the HLA system [1, 2]. In this single center study, we retrospectively deal with those donor factors and propose a modified management fo donor-recipient selection.

Keywords

Brain Death Graft Survival Rate Donor Factor Organ Harvesting Histocompatibility System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Cecka JM (1987) Donor factors. In: Terasaki PJ (ed) Clinical transplants 1987. UCLA Tissue Typing Laboratory, Los Angeles, California.Google Scholar
  2. 2.
    Lucas BA, Vaughn WK, Spees EK, Sanfilippo F (1987) Identification of donor factors predisponing to high discard rates of cadaver kidneys and increased graft loss within one year posttransplantation — SEOPF 1977–1982. Transplantation 42:253–258.CrossRefGoogle Scholar
  3. 3.
    Terasaki PI, Mickey MR, Cecka M, Cicciarelli J, Cook D, Iwaki Y, Toyotome A, Wang L (1987) Overview. In: Terasaki PJ (ed) Clinical transplants 1987. UCLA Tissue Typing Laboratory, Los Angeles, California.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • W. Niebel
    • 1
  • K. H. Albrecht
    • 1
  • A. Gille
    • 1
  • K. Wagner
    • 2
  • F. W. Eigler
    • 1
  • H. Grosse-Wilde
    • 3
  • J. Erhard
    • 1
  • A. Daul
    • 2
  • T. Philipp
    • 2
  1. 1.Department of General SurgeryUniversity Clinic EssenEssen 1Germany
  2. 2.Department of NephrologyUniversity Clinic EssenEssen 1Germany
  3. 3.Department of ImmunogeneticsUniversity Clinic EssenEssen 1Germany

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